Position-dependent, hyperexcitable patellar reflex dynamics in chronic stroke

Abstract

Objectives: To quantify tendon tap response (TTR) properties and their position dependence using multiple neuromechanical parameters, and to analyze correlations among neuromechanical and clinical measures.

Design: Hyperexcitable dynamics of TTR were investigated in a case-control manner. An instrumented hammer was used to induce the patellar deep tendon reflex (DTR), with reflex-mediated electromyography and torque responses measured across a range of knee flexion.

Setting: Research laboratory in a rehabilitation hospital.

Participants: Chronic hemiplegic stroke survivors (n=9) and healthy subjects (n=13).

Interventions: Not applicable.

Main Outcome Measures: Neuromechanical measures (system gain, contraction rate, half-relaxation rate, reflex loop delay, peak reflex torque, peak reflex electromyography, and reflex threshold in tapping force) were measured to characterize neuromuscular properties of patellar T"TR. Clinical measurements were taken using the DTR scale and the Modified Ashworth Scale.

Results: The system gain, contraction rate, half-relaxation rate, and peak reflex-mediated torque in the stroke group were generally higher, whereas the reflex threshold in the stroke group was significantly lower than their counterparts in the control group across 450 to 90 of knee flexion (P<.05). The 4 parameters were significantly higher at 60 degrees and 75 degrees of flexion than at 15 degrees, 30 degrees, 45 degrees, and 90 degrees, and their correlations with the 2 clinical scales at 60 degrees, 75 degrees, and 90 degrees of flexion were also significantly higher than those at 15 degrees, 30 degrees, and 45 degrees (P<.05).

Conclusions: The results showed hyperexcitability of TTR in stroke, quantified using a number of neuromechanical measures. Those measures peak around 60 degrees to 75 degrees of knee flexion and were correlated with clinical scales. Archives of Physical Medicine and Rehabilitation 2013;94:391-400 (C) 2013 by the American Congress of Rehabilitation Medicine