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Kang, Hyun-Wook
3D Biofabrication Lab (3BL)
Research Interests
  • 3D Bioprinting, tissue engineering and regenerative medicine, Body-on-a-chip

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Improvement of the representative volume element method for 3-D scaffold simulation

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Title
Improvement of the representative volume element method for 3-D scaffold simulation
Other Titles
Improvement of the representative volume element method for 3-D scaffold simulation
Author
Cheng, Lv-ShaKang, Hyun-WookCho, Dong-Woo
Keywords
tissue engineering; scaffold; RVE model; FEM; microstereolithography technology
Issue Date
2006-10
Publisher
KOREAN SOC MECHANICAL ENGINEERS
Citation
JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY, v.20, no.10, pp.1722 - 1729
Abstract
Predicting the mechanical properties of the 3-D scaffold using finite element method (FEM) simulation is important to the practical application of tissue engineering. However, the porous structure of the scaffold complicates computer simulations, and calculating scaffold models at the pore level is time-consuming. In some cases, the demands of the procedure are too high for a computer to run the standard code. To address this problem, the representative volume element (RVE) theory was introduced, but studies on RVE modeling applied to the 3-D scaffold model have not been focused. In this paper, we propose an improved FEM-based RVE modeling strategy to better predict the mechanical properties of the scaffold prior to fabrication. To improve the precision of RVE modeling, we evaluated various RVE models of newly designed 3-D scaffolds using FEM simulation. The scaffolds were then constructed using microstereolithography technology, and their mechanical properties were measured for comparison
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DOI
10.1007/BF02916276
ISSN
1738-494X
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BME_Journal Papers
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