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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 241 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 233 | - |
dc.citation.title | BIOMEDICAL MICRODEVICES | - |
dc.citation.volume | 10 | - |
dc.contributor.author | Lee, Seung-Jae | - |
dc.contributor.author | Kang, Hyun-Wook | - |
dc.contributor.author | Park, Jung Kyu | - |
dc.contributor.author | Rhie, Jong-Won | - |
dc.contributor.author | Hahn, Sei Kwang | - |
dc.contributor.author | Cho, Dong-Woo | - |
dc.date.accessioned | 2023-12-22T08:41:28Z | - |
dc.date.available | 2023-12-22T08:41:28Z | - |
dc.date.created | 2015-08-04 | - |
dc.date.issued | 2008-04 | - |
dc.description.abstract | Conventional methods for fabricating three-dimensional (3-D) tissue engineering scaffolds have substantial limitations. In this paper, we present a method for applying microstereolithography in the construction of 3-D cartilage scaffolds. The system provides the ability to fabricate scaffolds having a pre-designed internal structure, such as pore size and porosity, by stacking photopolymerized materials. To control scaffold structure, CAD/CAM technology was used to generate a scaffold pattern algorithm. Since tissue scaffolds must be constructed using a biocompatible, biodegradable material, scaffolds were synthesized using liquid photocurable TMC/TMP, followed by acrylation at the terminal ends, and photocured under UV light irradiation. The solidification properties of the TMC/TMP polymer were also assessed. To assess scaffold functionality, chondrocytes were seeded on two types of 3-D scaffold and characterized for cell adhesion. Results indicate that scaffold geometry plays a critical role in chondrocyte adhesion, ultimately affecting the tissue regeneration utility of the scaffolds. These 3-D scaffolds could eventually lead to optimally designed constructs for the regeneration of various tissues, such as cartilage and bone | - |
dc.identifier.bibliographicCitation | BIOMEDICAL MICRODEVICES, v.10, no.2, pp.233 - 241 | - |
dc.identifier.doi | 10.1007/s10544-007-9129-4 | - |
dc.identifier.issn | 1387-2176 | - |
dc.identifier.scopusid | 2-s2.0-40349086893 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/13345 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs10544-007-9129-4 | - |
dc.identifier.wosid | 000253525500011 | - |
dc.language | 영어 | - |
dc.publisher | SPRINGER | - |
dc.title.alternative | Application of microstereolithography in the development of three-dimensional cartilage regeneration scaffolds | - |
dc.title | Application of microstereolithography in the development of three-dimensional cartilage regeneration scaffolds | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | microstereolithography | - |
dc.subject.keywordAuthor | scaffold | - |
dc.subject.keywordAuthor | chondrocyte | - |
dc.subject.keywordAuthor | CAD/CAM | - |
dc.subject.keywordPlus | CARBONATE-BASED PREPOLYMERS | - |
dc.subject.keywordPlus | MICRO-STEREOLITHOGRAPHY | - |
dc.subject.keywordPlus | DESIGN | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | CONSTRUCTS | - |
dc.subject.keywordPlus | TISSUES | - |
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