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DC Field | Value | Language |
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dc.citation.endPage | 987 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 978 | - |
dc.citation.title | BIOINFORMATICS | - |
dc.citation.volume | 16 | - |
dc.contributor.author | Bhak, Jong Hwa | - |
dc.contributor.author | Dietmann, Sabine | - |
dc.contributor.author | Heger, Andreas | - |
dc.contributor.author | Holm, Liisa | - |
dc.date.accessioned | 2023-12-22T12:06:32Z | - |
dc.date.available | 2023-12-22T12:06:32Z | - |
dc.date.created | 2015-08-03 | - |
dc.date.issued | 2000-11 | - |
dc.description.abstract | Motivation: How critical is the sequence order information in predicting protein secondary structure segments? We tried to get a rough insight on it from a theoretical approach using both a prediction algorithm and structural fragments from Protein Databank (PDB). Results: Using reverse protein sequences and PDB structural fragments, we theoretically estimated the significance of the order for protein secondary structure and prediction. On average: (1) 79% of protein sequence segments resulted in the same prediction in both normal and reverse directions, which indicated a relatively high conservation of secondary structure propensity in the reverse direction; (2) the reversed sequence prediction alone performed less accurately than the normal forward sequence prediction, but comparably high (2% difference); (3) the commonly predicted regions showed a slightly higher prediction accuracy (4%) than the normal sequences prediction; and (4) structural fragments which have counterparts in reverse direction in the same protein showed a comparable degree of secondary structure conservation (73% identity with reversed structures on average for pentamers) | - |
dc.identifier.bibliographicCitation | BIOINFORMATICS, v.16, no.11, pp.978 - 987 | - |
dc.identifier.doi | 10.1093/bioinformatics/16.11.978 | - |
dc.identifier.issn | 1367-4803 | - |
dc.identifier.scopusid | 2-s2.0-0034521885 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/13251 | - |
dc.identifier.url | http://bioinformatics.oxfordjournals.org/content/16/11/978 | - |
dc.identifier.wosid | 000166343700004 | - |
dc.language | 영어 | - |
dc.publisher | OXFORD UNIV PRESS | - |
dc.title.alternative | Estimating the significance of sequence order in protein secondary structure and prediction. | - |
dc.title | Estimating the significance of sequence order in protein secondary structure and prediction | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scopus | - |
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