File Download

There are no files associated with this item.

  • Find it @ UNIST can give you direct access to the published full text of this article. (UNISTARs only)
Related Researcher

박종화

Bhak, Jong
KOrean GenomIcs Center
Read More

Views & Downloads

Detailed Information

Cited time in webofscience Cited time in scopus
Metadata Downloads

SNP@Promoter: a database of human SNPs (Single Nucleotide Polymorphisms) within the putative promoter regions

Alternative Title
SNP@Promoter: A database of human SNPs (Single Nucleotide Polymorphisms) within putative promoter region.
Author(s)
Kim, Byoung-ChulKim, Woo-YeonPark, DaeuiChung, Won-HyongShin, KwangsikBhak, Jong Hwa
Issued Date
2008-02
DOI
10.1186/1471-2105-9-S1-S2
URI
https://scholarworks.unist.ac.kr/handle/201301/13189
Fulltext
http://www.biomedcentral.com/1471-2105/9/S1/S2
Citation
BMC BIOINFORMATICS, v.9, no.S2, pp.SUPPL. 1
Abstract
Background: Analysis of single nucleotide polymorphism (SNP) is becoming a key research in genomics fields. Many functional analyses of SNPs have been carried out for coding regions and splicing sites that can alter proteins and mRNA splicing. However, SNPs in non-coding regulatory regions can also influence important biological regulation. Presently, there are few databases for SNPs in non-coding regulatory regions. Description: We identified 488,452 human SNPs in the putative promoter regions that extended from the +5000 bp to -500 bp region of the transcription start sites. Some SNPs occurring in transcription factor (TF) binding sites were also predicted (47,832 SNP; 9.8%). The result is stored in a database: SNP@promoter. Users can search the SNP@Promoter database using three entries: 1) by SNP identifier (rs number from dbSNP), 2) by gene (gene name, gene symbol, refSeq ID), and 3) by disease term. The SNP@Promoter database provides extensive genetic information and graphical views of queried terms. Conclusion: We present the SNP@Promoter database. It was created in order to predict functional SNPs in putative promoter regions and predicted transcription factor binding sites. SNP@Promoter will help researchers to identify functional SNPs in non-coding regions
Publisher
BIOMED CENTRAL LTD
ISSN
1471-2105
Keyword
TRANSCRIPTION FACTOR-BINDINGCIS-REGULATORY MODULESRSNP-GUIDESITESELEMENTSDNASYSTEMGENOMEGENEASSOCIATION

qrcode

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.