dc.citation.endPage |
196 |
- |
dc.citation.number |
3 |
- |
dc.citation.startPage |
189 |
- |
dc.citation.title |
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS |
- |
dc.citation.volume |
6 |
- |
dc.contributor.author |
Kim, Seong-Jin |
- |
dc.contributor.author |
Yoon, Euisik |
- |
dc.date.accessioned |
2023-12-22T05:07:48Z |
- |
dc.date.available |
2023-12-22T05:07:48Z |
- |
dc.date.created |
2015-07-16 |
- |
dc.date.issued |
2012-06 |
- |
dc.description.abstract |
We present a label-free CMOS field-effect transistor sensing array to detect the surface potential change affected by the negative charge in DNA molecules for real-time monitoring and quantification. The proposed CMOS bio sensor includes a new sensing pixel architecture implemented with correlated double sampling for reducing offset fixed pattern noise and 1/f noise of the sensing devices. We incorporated non-surface binding detection which allows real-time continuous monitoring of DNA concentrations without immobilizing them on the sensing surface. Various concentrations of 19-bp oligonucleotides solution can be discriminated using the prototype device fabricated in 1-μm double-poly double-metal standard CMOS process. The detection limit was measured as 1.1 ng/μl with a dynamic range of 40 dB and the transient response time was measured less than 20 seconds. © 2011 IEEE. |
- |
dc.identifier.bibliographicCitation |
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, v.6, no.3, pp.189 - 196 |
- |
dc.identifier.doi |
10.1109/TBCAS.2011.2172992 |
- |
dc.identifier.issn |
1932-4545 |
- |
dc.identifier.scopusid |
2-s2.0-84861756462 |
- |
dc.identifier.uri |
https://scholarworks.unist.ac.kr/handle/201301/12290 |
- |
dc.identifier.url |
http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6095639 |
- |
dc.identifier.wosid |
000304606900001 |
- |
dc.language |
한국어 |
- |
dc.publisher |
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC |
- |
dc.title |
Label-free CMOS Bio Sensor with On-chip Noise Reduction Scheme for Real-time Quantitative Monitoring of Biomolecules |
- |
dc.type |
Article |
- |
dc.description.journalRegisteredClass |
scie |
- |
dc.description.journalRegisteredClass |
scopus |
- |