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TRAP1 binds to glutamine synthetase and might affect cancer cell metabolism

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Title
TRAP1 binds to glutamine synthetase and might affect cancer cell metabolism
Author
Lim, Hakmyeong
Advisor
Kang, Byoung Heon
Keywords
TRAP1; GS; Glutamine; Cancer
Issue Date
2015-02
Publisher
Graduate school of UNIST
Abstract
TRAP1 is anti-apoptotic mitochondrial protein. There have been implications about this chaperone and cancer cell metabolism but it is not known how TRAP1 affects. Glutamine synthetase is a candidate of TRAP1 binding protein in this study. GS is well known as ammonia detoxifying function. This paper will deal with 2 proteins’ binding and their role in cancer cell metabolism.
Description
Department of Biological Sciences
URI
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