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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 189 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 187 | - |
dc.citation.title | ORGANIC LETTERS | - |
dc.citation.volume | 17 | - |
dc.contributor.author | Kee, Jung-Min | - |
dc.contributor.author | Oslund, Rob C. | - |
dc.contributor.author | Couvillon, Anthony D. | - |
dc.contributor.author | Muir, Tom W. | - |
dc.date.accessioned | 2023-12-22T01:43:37Z | - |
dc.date.available | 2023-12-22T01:43:37Z | - |
dc.date.created | 2015-02-02 | - |
dc.date.issued | 2015-01 | - |
dc.description.abstract | Protein histidine phosphorylation plays a crucial role in cell signaling and central metabolism. However, its detailed functions remain elusive due to technical challenges in detecting and isolating proteins bearing phosphohistidine (pHis), a labile posttranslational modification (PTM). To address this issue, we previously developed the first pHis-specific antibodies using stable, synthetic triazole-based pHis analogs. A second-generation, pyrazole-based pHis analog that enabled the development of a pan-pHis antibody with much improved pHis specificity is now reported. | - |
dc.identifier.bibliographicCitation | ORGANIC LETTERS, v.17, no.2, pp.187 - 189 | - |
dc.identifier.doi | 10.1021/ol503320p | - |
dc.identifier.issn | 1523-7060 | - |
dc.identifier.scopusid | 2-s2.0-84921310093 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/10401 | - |
dc.identifier.url | http://pubs.acs.org/doi/abs/10.1021/ol503320p | - |
dc.identifier.wosid | 000348331800005 | - |
dc.language | 영어 | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | A second-generation phosphohistidine analog for production of phosphohistidine antibodies | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | PHOSPHORYLATION | - |
dc.subject.keywordPlus | PROTEINS | - |
dc.subject.keywordPlus | RESIDUES | - |
dc.subject.keywordPlus | FOCUS | - |
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