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DC Field | Value | Language |
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dc.citation.endPage | 200 | - |
dc.citation.startPage | 193 | - |
dc.citation.title | HEARING RESEARCH | - |
dc.citation.volume | 301 | - |
dc.contributor.author | Nguyen, Cac T. | - |
dc.contributor.author | Robinson, Sarah R. | - |
dc.contributor.author | Jung, Woonggyu | - |
dc.contributor.author | Novak, Michael A. | - |
dc.contributor.author | Boppart, Stephen A. | - |
dc.contributor.author | Allen, Jont B. | - |
dc.date.accessioned | 2023-12-22T03:41:46Z | - |
dc.date.available | 2023-12-22T03:41:46Z | - |
dc.date.created | 2015-01-27 | - |
dc.date.issued | 2013-07 | - |
dc.description.abstract | Children with chronic otitis media (OM) often have conductive hearing loss which results in communication difficulties and requires surgical treatment. Recent studies have provided clinical evidence that there is a one-to-one correspondence between chronic OM and the presence of a bacterial biofilm behind the tympanic membrane (TM). Here we investigate the acoustic effects of bacterial biofilms, confirmed using optical coherence tomography (OCT), in adult ears. Non-invasive OCT images are collected to visualize the cross-sectional structure of the middle ear, verifying the presence of a biofilm behind the TM. Wideband measurements of acoustic reflectance and impedance (0.2e6 [kHz]) are used to study the acoustic properties of ears with confirmed bacterial biofilms. Compared to known acoustic properties of normal middle ears, each of the ears with a bacterial biofilm has an elevated power reflectance in the 1 to 3 [kHz] range, corresponding to an abnormally small resistance (real part of the impedance). These results provide assistance for the clinical diagnosis of a bacterial biofilm, which could lead to improved treatment of chronic middle ear infection and further understanding of the impact of chronic OM on conductive hearing loss |
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dc.identifier.bibliographicCitation | HEARING RESEARCH, v.301, pp.193 - 200 | - |
dc.identifier.doi | 10.1016/j.heares.2013.04.001 | - |
dc.identifier.issn | 0378-5955 | - |
dc.identifier.scopusid | 2-s2.0-84878590097 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/10328 | - |
dc.identifier.wosid | 000320478100023 | - |
dc.language | 영어 | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.title | Investigation of bacterial biofilm in the human middle ear using optical coherence tomography and acoustic measurements | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | CONDUCTIVE HEARING-LOSS | - |
dc.subject.keywordPlus | OTITIS-MEDIA | - |
dc.subject.keywordPlus | REFLECTANCE MEASUREMENTS | - |
dc.subject.keywordPlus | ENERGY REFLECTANCE |
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dc.subject.keywordPlus | CANAL REFLECTANCE | - |
dc.subject.keywordPlus | UMBO VELOCITY | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | MUCOSA | - |
dc.subject.keywordPlus | TYMPANOMETRY | - |
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