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Showing results 1 to 20 of 22

Issue DateTitleAuthor(s)TypeView
2015-11A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular MechanismsDerrick, Jeffrey S.; Kerr, Richard A.; Nam, Younwoo; Oh, Shin Bi; Lee, Hyuck Jin; Earnest, Kaylin G.; Suh, Nayoung; Peck, Kristy L.; Ozbil, Mehmet; Korshavn, Kyle J.; Ramamoorthy, Ayyalusamy; Prabhakar, Rajeev; Merino, Edward J.; Shearer, Jason; Lee, Joo-Yong; Ruotolo, Brandon T.; Lim, Mi HeeARTICLE573
2014-05A small molecule that displays marked reactivity toward copper-versus zinc-amyloid-β implicated in Alzheimer's diseaseSavelieff, Masha G.; Liu, Yuzhong; Senthamarai, Russell R. P.; Korshavn, Kyle J.; Lee, Hyuck Jin; Ramamoorthy, Ayyalusamy; Lim, Mi HeeARTICLE484
2016-01Amyloid-beta adopts a conserved, partially folded structure upon binding to zwitterionic lipid bilayers prior to amyloid formationLim, Mi Hee; Korshavn, Kyle J.; Ramamoorthy, Ayyalusamy; Bhunia, AnirbanARTICLE503
2017-01An Iridium(III) Complex as a Photoactivatable Tool for Oxidation of Amyloidogenic Peptides with Subsequent Modulation of Peptide AggregationKang, Juhye; Lee, Shin Jung C.; Nam. Jung Seung; Lee, Hyuck Jin; Kang, Mueong-G.; Korshavn, Kyle J.; Kim, Hyun-Tak; Cho, Jaeheung; Ramamoorthy, Ayyalusamy; Rhee, Hyun-Woo; Kwon, Tae-Hyuk; Lim, Mi HeeARTICLE485
2016-07Biophysical insights into the membrane interaction of the core amyloid-forming A beta(40) fragment K16-K28 and its role in the pathogenesis of Alzheimer's diseaseBera, Swapna; Korshavn, KJ; Kar, Rajjiv K.; Lim, Mi Hee; Ramamoorthy, Ayyalusamy; Bhunia, AnirbanARTICLE559
2010-12Design of small molecules that target metal-A beta species and regulate metal-induced A beta aggregation and neurotoxicityChoi, Jung-Suk; Braymer, Joseph J.; Nanga, Ravi P. R.; Ramamoorthy, Ayyalusamy; Lim, Mi HeeARTICLE492
2011-11Development of Bifunctional Stilbene Derivatives for Targeting and Modulating Metal-Amyloid-beta SpeciesBraymer, Joseph J.; Choi, Jung-Suk; DeToma, Alaina S.; Wang, Chen; Nam, Kisoo; Kampf, Jeffrey W.; Ramamoorthy, Ayyalusamy; Lim, Mi HeeARTICLE428
2019-08Diverse Structural Conversion and Aggregation Pathways of Alzheimer's Amyloid-beta (1-40)Lin, Yuxi; Sahoo, Bikash R.; Ozawa, Daisaku; Kinoshita, Misaki; Kang, Juhye; Lim, Mi Hee; Okumura, Masaki; Huh, Yang Hoon; Moon, Eunyoung; Jang, Jae Hyuck; Lee, Hyun-Ju; Ryu, Ka-Young; Ham, Sihyun; Wong, Haing-Sik; Ryu, Kyoung-Seok; Sugiki, Toshihiko; Bang, Jeong Kyu; Hoe, Hyang-Sook; Fujiwara, Toshimichi; Ramamoorthy, Ayyalusamy; Lee, Young-HoARTICLE0
2012-08Dual-function triazole-pyridine derivatives as inhibitors of metal-induced amyloid-beta aggregationJones, Michael R.; Service, Erin L.; Thompson, John R.; Wang, Michael C. P.; Kimsey, Isaac J.; DeToma, Alaina S.; Ramamoorthy, Ayyalusamy; Lim, Mi Hee; Storr, TimARTICLE488
2016-03Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregationLee, Hyuckjin; Kerr, Richard A.; Korshavn, Kyle J.; Lee, Jeeyeon; Kang, Juhye; Ramamoorthy, Ayyalusamy; Ruotolo, Brandon T.; Lim, Mi HeeARTICLE605
2016-05Importance of the Dimethylamino Functionality on a Multifunctional Framework for Regulating Metals, Amyloid-beta, and Oxidative Stress in Alzheimer's DiseaseDerrick, Jeffry S.; Kerr, Richard A.; Korshavn, Kyle J.; McLane, Michael J.; Kang, Juhye; Nam, Eunju; Ramamoorthy, Ayyalusamy; Ruotolo, Brandon T.; Lim, Mi HeeARTICLE454
2013-03Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-beta speciesHyung, Suk-Joon; DeToma, Alaina S.; Brender, Jeffrey R.; Lee, Sanghyun; Vivekanandan, Subramanian; Kochi, Akiko; Choi, Jung-Suk; Ramamoorthy, Ayyalusamy; Ruotolo, Brandon T.; Lim, Mi HeeARTICLE502
2014-12Interaction and reactivity of synthetic aminoisoflavones with metal-free and metal-associated amyloid-βDetoma, Alaina S.; Krishnamoorthy, Janarthanan; Nam, Younwoo; Lee, Hyuck Jin; Brender, Jeffrey R.; Kochi, Akiko; Lee, Dongkuk; Onnis, Valentina; Congiu, Cenzo; Manfredini, Stefano; Vertuani, Silvia; Balboni, Gianfranco; Ramamoorthy, Ayyalusamy; Lim, Mi HeeARTICLE615
2017-11Minor Structural Variations of Small Molecules Tune Regulatory Activities Towards Pathological Factors in Alzheimer’s DiseaseBeck, Michael W.; Derrick, Jeffrey S.; Suh, Jong-Min; Kim, Mingeun; Korshavn, Kyle J.; Kerr, Richard A.; Cho, Woo Jong; Larsen, Scott D.; Ruotolo, Brandon T.; Ramamoorthy, Ayyalusamy; Lim, Mi HeeARTICLE232
2012-01Misfolded proteins in Alzheimer's disease and type II diabetesDeToma, Alaina S.; Salamekh, Samer; Ramamoorthy, Ayyalusamy; Lim, Mi HeeARTICLE447
2017-08Multi-target-directed phenol-triazole ligands as therapeutic agents for Alzheimer's diseaseJones, Michael R.; Mathieu, Emilie; Dyrager, Christine; Faissner, Simon; Vaillancourt, Zavier; Korshavn, Kyle J.; Lim, Mi Hee; Ramamoorthy, Ayyalusamy; Yong, V. Wee; Tsutsui, Shigeki; Stys, Peter K.; Storr, TimARTICLE234
2014-01Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's diseaseLee, Sanghyun; Zheng, Xueyun; Krishnamoorthy, Janarthanan; Savelieff, Masha G.; Park, Hyun Min; Brender, Jeffrey R.; Kim, Jin Hoon; Derrick, Jeffrey S.; Kochi, Akiko; Lee, Hyuck Jin; Kim, Cheal; Ramamoorthy, Ayyalusamy; Bowers, Michael T.; Lim, Mi HeeARTICLE564
2015-12Reactivity of Metal-Free and Metal-Associated Amyloid-β with Glycosylated Polyphenols and Their Esterified DerivativesKorshavn, Kyle J.; Jang, Milim; Kwak, Yeon Ju; Kochi, Akiko; Vertuani, Silvia; Bhunia, Anirban; Manfredini, Stefano; Ramamoorthy, Ayyalusamy; Lim, Mi HeeARTICLE667
2017-03Reduced lipid bilayer thickness regulates the aggregation and cytotoxicity of amyloid-βKorshavn, Kyle J.; Satriano, Cristina; Lin, Yuxi; Zhang, Rongchun; Dulchavsky, Mark; Bhunia, Anirban; Ivanova, Magdalena I.; Lee, Young-Ho; Rosa, Carmelo La; Lim, Mi Hee; Ramamoorthy, AyyalusamyARTICLE303
2009-11Small Molecule Modulators of Copper-Induced A beta AggregationHindo, Sarmad S.; Mancino, Allana M.; Braymer, Joseph J.; Liu, Yihong; Vivekanandan, Subramanian; Ramamoorthy, Ayyalusamy; Lim, Mi HeeARTICLE611
Showing results 1 to 20 of 22