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Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity File

Yang, Sujae , Yoon, Nam Gu , Kim, Dongyoung , Park, Eunsun , Kim, So-Yeon , Lee, Ji Hoon , Lee, Changwook , Kang, Byoung Heon , Kang, Soosung

Article Issue Date2021-07 View81
Development of a Fluorescence Probe for High-Throughput Screening of Allosteric Inhibitors Targeting TRAP1 File

Yoon, Nam Gu , Choi, Danbi , Lee, Ji Hye , Kim, So-Yeon , Im, Jin Young , Yun, Jisu , Yang, Sujae , Kim, Taeeun , Kang, Soosung , Kang, Byoung Heon

Article Issue Date2024-12 View54
Development of Hsp90 family protein inhibitors

Park, Hye-Kyung , Ko, Eunhwa , Lee, Geumwoo , Lee, Ji-Eun , Lee, Sang Kwang , Jeong, Hanbin , Lee, An-Jung , Im, Jin Young , Kim, Seong Heon , Lee, Changwook , et al

Conference Paper Issue Date2016-12-09 View33
Development of mitochondria-targeted Hsp90 inhibitor as a anti-cancer drug

Park, Hye-Jyung , Ko, Eunhwa , Lee, Gemwoo , Lee, Ji-Eun , Lee, Sang Kwang , Jeong, Hanbin , Lee, An-Jung , Im, Jing Young , Hu, Sung , Kim, Seong Heon , et al

Conference Paper Issue Date2016-11-25 View23
Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models File

Kim, Darong , Kim, So-Yeon , Kim, Dongyoung , Yoon, Nam Gu , Yun, Jisu , Hong, Ki Bum , Lee, Changwook , Lee, Ji Hoon , Kang, Byoung Heon , Kang, Soosung

Article Issue Date2020-08 View100
Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1 File

Jung, Sejin , Yoon, Nam Gu , Yang, Sujae , Kim, Darong , Lee, Won Seok , Hong, Ki Bum , Lee, Changwook , Kang, Byoung Heon , Lee, Ji Hoon , Kang, Soosung

Article Issue Date2020-01 View68
Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site File

Yoon, Nam Gu , Lee, Hakbong , Kim, So-Yeon , Hu, Sung , Kim, Darong , Yang, Sujae , Hong, Ki Bum , Lee, Ji Hoon , Kang, Soosung , Kim, Byung-Gyu , et al

Article Issue Date2021-12 View105
Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors

Park, Hye-Kyung , Jeong, Hanbin , Ko, Eunhwa , Lee, Geunwoo , Lee, Ji-Eun , Lee, Sang Kwang , Lee, An-Jung , Lee, Jin Young , Hu, Sung , Kin, Seong Heon , et al

Conference Paper Issue Date2018-06-28 View35
Triphenylphosphonium conjugation to a TRAP1 inhibitor, 2-amino-6--chloro-7,9-dihydro-8H-purin-8-one increases antiproliferative activity File

Yang, Sujae , Yoon, Nam Gu , Park, Min-A , Yun, Jisu , Im, Jin Young , Kang, Byoung Heon , Kang, Soosung

Article Issue Date2022-09 View102
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