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Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade File

Savelieff, Masha G. , Nam, Geewoo , Kang, Juhye , Lee, Hyuck Jin , Lee, Misun , Lim, Mi Hee

Article Issue Date2019-01 View3

Effects of Variable Hydroxyl Groups on the Flavonoid Backbone toward Modulation of Metal–Amyloid-Beta Aggregation Pathways

Lim, Mi Hee , Lee, Hyuck Jin , Kerr, Richard A. , Korshavn, Kyle J. , Lee, Jeeyeon , Ramamoorthy, Ayyalusamy , Ruotolo, Brandon T.

Conference Paper Issue Date2015-08-12 View1

Flavonoids: Redirection of Metal-Free and Metal-Associated Amyloid-b Aggregation Into Nontoxic, Off-Pathway Amorphous Peptide Aggregates

Lim, Mi Hee , DeToma, Alaina S. , Lee, Hyuck Jin , Lee, Jeeyeon

Conference Paper Issue Date2014-12-01 View3

Impact of sphingosine and acetylsphingosines on the aggregation and toxicity of metal-free and metal-treated amyloid-beta File

Yi, Yelim , Lin, Yuxi , Han, Jiyeon , Lee, Hyuck Jin , Park, Nahye , Nam, Geewoo , Park, Young S. , Lee, Young-Ho , Lim, Mi Hee

Article Issue Date2021-02 View7

Inhibitory activity of curcumin derivatives towards metal-free and metal-induced amyloid-β aggregation File

Kochi, Akiko , Lee, Hyuck Jin , Vithanarachchi, Sashiprabha M. , Padmini, Vediappen , Allen, Matthew J. , Lim, Mi Hee

Article Issue Date2015-05 View6

Interaction and reactivity of synthetic aminoisoflavones with metal-free and metal-associated amyloid-β File

Detoma, Alaina S. , Krishnamoorthy, Janarthanan , Nam, Younwoo , Lee, Hyuck Jin , Brender, Jeffrey R. , Kochi, Akiko , Lee, Dongkuk , Onnis, Valentina , Congiu, Cenzo , Manfredini, Stefano , et al

Article Issue Date2014-12 View6

Mechanistic approaches for chemically modifying the coordination sphere of copper-amyloid-beta complexes File

Han, Jiyeon , Lee, Hyuck Jin , Kim, Kyu Yeon , Nam, Geewoo , Chae, Junghyun , Lim, Mi Hee

Article Issue Date2020-03 View4

Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in Dementia File

Kim, Mingeun , Kang, Juhye , Lee, Misun , Han, Jiyeon , Nam, Geewoo , Tak, Eunyoung , Kim, Min Sun , Lee, Hyuck Jin , Nam, Eunju , Park, Jiyong , et al

Article Issue Date2020-05 View5

Molecular Insights into Human Serum Albumin as a Receptor of Amyloid-β in the Extracellular Region File

Choi, Tae Su , Lee, Hyuck Jin , Han, Jong Yoon , Lim, Mi Hee , Kim, Hugh I.

Article Issue Date2017-11 View3

Monitoring metal–amyloid-β complexation by a FRET-based probe: design, detection, and inhibitor screening File File

Lee, Hyuck Jin , Lee, Young Geun , Kang, Juhye , Yang, Seung Hyun , Kim, Ju Hwan , Ghisaidoobe, Amar B. T. , Kang, Hyo Jin , Lee, Sang-Rae , Lim, Mi Hee , Chung, Sang J.

Article Issue Date2019-01 View4

Multiple reactivities of flavonoids towards pathological elements in Alzheimer's disease: structure-activity relationship File

Nam, Geewoo , Hong, Mannkyu , Lee, Juri , Lee, Hyuck Jin , Ji, Yonghwan , Kang, Juhye , Baik, Mu-Hyun , Lim, Mi Hee

Article Issue Date2020-10 View1

Orobol: An Isoflavone Exhibiting Regulatory Multifunctionality against Four Pathological Features of Alzheimer's Disease File

Nam, Geewoo , Ji, Yonghwan , Lee, Hyuck Jin , Kang, Juhye , Yi, Yelim , Kim, Mingeun , Lin, Yuxi , Lee, Young-Ho , Lim, Mi Hee

Article Issue Date2019-08 View3

Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease File

Lee, Sanghyun , Zheng, Xueyun , Krishnamoorthy, Janarthanan , Savelieff, Masha G. , Park, Hyun Min , Brender, Jeffrey R. , Kim, Jin Hoon , Derrick, Jeffrey S. , Kochi, Akiko , Lee, Hyuck Jin , et al

Article Issue Date2014-01 View5

Redox-tuning of Small Molecules to Develop Chemical Regulators for Multiple Pathogenic Elements in Alzheimer’s Disease

Han, Jiyeon , Lee, Hyuck Jin , Cho, Jaeheung , Chae, Junghyun , Lim, Mi Hee

Conference Paper Issue Date2017-10-18 View3

Redox-tuning of Small Molecules to Develop Chemical Regulators for Multiple Pathogenic Elements in Alzheimer’s Disease

Han, Jiyeon , Lee, Hyuck Jin , Cho, Jaeheung , Chae, Junghyun , Lim, Mi Hee

Conference Paper Issue Date2017-10-19 View4

Strategic Design of 2,2 '-Bipyridine Derivatives to Modulate Metal Amyloid-beta Aggregation File

Ji, Yonghwan , Lee, Hyuck Jin , Kim, Munjeong , Nam, Geewoo , Lee, Shun Jung C. , Cho. Jaeheung , Park, Cheol-Min , Lim, Mi Hee

Article Issue Date2017-06 View8

Strategic Design of 2,2’-Bipyridine Derivatives to Modulate Metal-Amyloid-β Aggregation

Ji, Yongwhan , Lee, Hyuck Jin , Cho, Jaeheung , Park, Cheol-Min , Lim, Mi Hee

Conference Paper Issue Date2017-10-19 View3

Strategic Design of 2,2’-Bipyridine Derivatives to Modulate Metal–Amyloid-beta Aggregation

Ji, Yonghwan , Lee, Hyuck Jin , Kim, Minjeong , Nam, Geewoo , Lee, Shin Jung C. , Cho, Jaeheung , Park, Cheol-Min , Lim, Mi Hee

Conference Paper Issue Date2017-07-19 View3

Strategic Design of 2,2’-Bipyridine Derivatives to Modulate Metal–Amyloid-beta Aggregation

Ji, Yonghwan , Lee, Hyuck Jin , Kim, Minjeong , Nam, Geewoo , Lee, Shin Jung C. , Cho, Jaeheung , Park, Cheol-Min , Lim, Mi Hee

Conference Paper Issue Date2017-08-16 View3

Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer’s Disease

Lee, Hyuck Jin , Korshavn, Kyle J , Nam, Younwoo , Paul, Thomas J. , Kerr, Richard A , Youn, Il Seung , Kang, Juhye , Ozbil, Mehmet , Kim, Kwang S. , Ruotolo, Brandon T , et al

Conference Paper Issue Date2017-08-16 View3

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