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Chae, Young Chan (채영찬)

Department
School of Life Sciences(생명과학부)
Research Interests
Cancer Metabolism, Stress Response of Cancer, Mitochondria of Cancer, Molecular Mechanisms of Cancer Initiation, Progression and Therapy, Autophagy in Cell Survival and Cancer Progression, Mechanism of tumor therapeutic resistance
Lab
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Issue DateTitleAuthor(s)TypeViewAltmetrics
201803Hypoxia-dependent mitochondrial fission regulates endothelial progenitor cell migration, invasion, and tube formationKim, Da Yeon; Jung, Seok Yun; Kim, Yeon Ju, et alARTICLE102 Hypoxia-dependent mitochondrial fission regulates endothelial progenitor cell migration, invasion, and tube formation
201802Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.Boucherat, Olivier; Peterlini, Thibaut; Bourgeois, Alice, et alARTICLE76 Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.
201801PLCγ1: Potential arbitrator of cancer progressionJang, Hyun-Jun; Suh, Pann-Ghill; Lee, Yu Jin, et alARTICLE147 PLCγ1: Potential arbitrator of cancer progression
201712A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapyBryant, Kelly G.; Chae, Young Chan; Martinez, Rogelio L., et alARTICLE103 A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy
201608Mitochondrial Akt Regulation of Hypoxic Tumor ReprogrammingChae, Young Chan; Vaira, Valentina; Caino, M. Cecilia, et alARTICLE156 Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming
201607The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and MetastasisSeo, Jae Ho; Rivadeneira, Dayana B.; Caino, M. Cecilia, et alARTICLE189 The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis
201605Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitorsZhang, Gao; Frederick, Dennie T.; Wu, Lawrence, et alARTICLE190 Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors
201603Pairwise detection of site-specific receptor phosphorylations using single-molecule blottingKim, Kyung Lock; Kim, Daehyung; Lee, Seongsil, et alARTICLE209 Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
201507PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasionCaino, M. Cecilia; Ghosh, Jagadish C.; Chae, Young Chan, et alARTICLE200 PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
201503Adaptive Mitochondrial Reprogramming and Resistance to PI3K TherapyGhosh, Jagadish C.; Siegelin, Markus D.; Vaira, Valentina, et alARTICLE102 Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy
201408Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic NetworksLisanti, Sofia; Tavecchio, Michele; Chae, Young Chan, et alARTICLE120 Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks
201307Landscape of the mitochondrial Hsp90 metabolome in tumoursChae, Young Chan; Angelin, Alessia; Lisanti, Sofia, et alARTICLE163 Landscape of the mitochondrial Hsp90 metabolome in tumours
201307Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cellsCaino, M. Cecilia; Chae, Young Chan; Vaira, Valentina, et alARTICLE170 Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells
201209Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90sChae, Young Chan; Caino, M. Cecilia; Lisanti, Sofia, et alARTICLE106 Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s
201011Protein Kinase C delta-Mediated Phosphorylation of Phospholipase D Controls Integrin-Mediated Cell SpreadingChae, Young Chan; Kim, Kyung Lock; Ha, Sang Hoon, et alARTICLE455 Protein Kinase C delta-Mediated Phosphorylation of Phospholipase D Controls Integrin-Mediated Cell Spreading
200912Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activityChae, Young Chan; Lee, Sukmook; Heo, Kyun, et alARTICLE498 Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activity
200811Hydrogen Peroxide-Induced VCAM-1 Expression in Pancreatic Islets and beta-Cells Through Extracellular Ca2+ InfluxLee, Sukmook; Ha, In Su; Kim, Jae Hyeon, et alARTICLE415 Hydrogen Peroxide-Induced VCAM-1 Expression in Pancreatic Islets and beta-Cells Through Extracellular Ca2+ Influx
200809Epidermal growth factor increases insulin secretion and lowers blood glucose in diabetic miceLee, H. Y.; Yea, K.; Kim, J., et alARTICLE340 Epidermal growth factor increases insulin secretion and lowers blood glucose in diabetic mice
200807Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membraneChae, Young Chan; Kim, Jung Hwan; Kim, Kyung Lock, et alARTICLE408 Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane
200612RGS2 promotes formation of neurites by stimulating microtubule polymerizationHeo, Kyun; Ha, Sang Hoon; Chae, Young Chan, et alARTICLE369 RGS2 promotes formation of neurites by stimulating microtubule polymerization

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