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Lee, Ja Yil

이자일

Department of Biological Sciences(생명과학과)

Biochemistry and Molecular Biophysics Lab.
Website

Research Interests: Biochemistry;molecular biophysics;biophysicochemical;분자메커니즘;생화학;생물물리학

Lab Description: We are studying molecular mechanisms underlying diverse DNA metabolic reactions such as DNA repair and chromatin dynamics using single-molecule DNA curtain as well as biophysicochemical methods.

Researcher ID Research Gate ORCiD Scopus Google Scholar

Impaired binding affinity of YTHDC1 with METTL3/METTL14 results in R-loop accumulation in myelodysplastic neoplasms with DDX41 mutation File File

Hwang, Won Chan , Park, Kibeom , Park, Silvia , Cheon, Na Young , Lee, Ja Yil , Hwang, Taejoo , Lee, Semin , Lee, Jong-Mi , Ju, Min Kyung , Lee, Joo Rak , et al

Article Issue Date2024-03 View46

Direct visualization of replication and R-loop collision using single-molecule imaging File File

Kim, Subin , Shin, Woo Hee , Kang, Yujin , Kim, Hongtae , Lee, Ja Yil

Article Issue Date2024-01 View15

Real-time single-molecule visualization using DNA curtains reveals the molecular mechanisms underlying DNA repair pathways File File

Kim, Subin , Kim, Youngseo , Lee, Ja Yil

Article Issue Date2024-01 View30

Alteration of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase File File

Kang, Yujin , Han, Ye Gi , Khim, Keon Woo , Choi, Woo Gyun , Ju, Min Kyung , Park, Kibeom , Shin, Kyeong Jin , Chae, Young Chan , Choi, Jang Hyun , Kim, Hongtae , et al

Article Issue Date2023-08 View19

MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1 File

Oh, Jung-Min , Kang, Yujin , Park, Jumi , Sung, Yubin , Kim, Dayoung , Seo, Yuri , Lee, EunA , Ra, JaeSun , Amarsanaa, Enkhzul , Park, Young-Un , et al

Article Issue Date2023-06 View24

ZNF212 promotes genomic integrity through direct interaction with TRAIP File File

Chung, Hee Jin , Lee, Joo Rak , Kim, Tae Moon , Kim, Soomi , Park, Kibeom , Kim, Myung-Jin , Jung, Eunyoung , Kim, Subin , Ra, Jae Sun , Hwang, Sunyoung , et al

Article Issue Date2023-01 View22

Single-molecule fluorescence imaging techniques reveal molecular mechanisms underlying deoxyribonucleic acid damage repair File File

Kang, Yujin , An, Soyeong , Min, Duyoung , Lee, Ja Yil

Article Issue Date2022-09 View17

PWWP2B promotes DNA end resection and homologous recombination File

Ju, Min Kyung , Lee, Joo Rak , Choi, Yeonsong , Park, Seon Young , Sul, Hee Jung , Chung, Hee Jin , An, Soyeong , Lee, Semin , Jung, Eungyoung , Kim, Bohyun , et al

Article Issue Date2022-07 View29

Deciphering Molecular Mechanism of Histone Assembly by DNA Curtain Technique File

Kang, Yujin , Bae, Subin , An, Soyeong , Lee, Ja Yil

Article Issue Date2022-03 View19

A novel high‑throughput single‑molecule technique: DNA curtain File

Cha, JongJin , Lee, Ja Yil

Article Issue Date2021-03 View15

Single-molecule imaging reveals the mechanism underlying histone loading of Schizosaccharomyces Pombe AAA+ ATPase Abo1 File File

Kang, Yujin , Cho, Carol , Lee, Kyung Suk , Song, Ji-Joon , Lee, Ja Yil

Article Issue Date2021-02 View13

TonEBP recognizes R-loops and initiates m6A RNA methylation for R-loop resolution File File

Kang, Hyun Je , Cheon, Na Young , Park, Hyun , Jeong, Gyu Won , Ye, Byeong Jin , Yoo, Eun Jin , Lee, Jun Ho , Hur, Jin-Hoe , Lee, Eun-A , Kim, Hongtae , et al

Article Issue Date2021-01 View21

High-throughput single-molecule imaging system using nanofabricated trenches and fluorescent DNA-binding proteins File

Kang, Yujin , Cheon, Na Young , Cha, Jongjin , Kim, Ayoung , Kim, Hyung-il , Lee, Luda , Kim, Kang O. , Jo, Kyubong , Lee, Ja Yil

Article Issue Date2020-06 View8

Glucosylceramide synthase regulates adipo‐osteogenic differentiation through synergistic activation of PPARγ with GlcCer File

Jang, Hyun-Jun , Lim, Seyoung , Kim, Jung-Min , Yoon, Sora , Lee, Chae Young , Hwang, Hyeon-Jeong , Shim, Jeong Woo , Shin, Kyeong Jin , Kim, Hye Yun , Park, Kwang Il , et al

Article Issue Date2020-01 View21

Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA File

Kang, Wooyoung , Ha, Kook Sun , Uhm, Heesoo , Park, Kyuhyong , Lee, Ja Yil , Hohng, Sungchul , Kang, Changwon

Article Issue Date2020-01 View12

Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone File File

Cho, Carol , Jang, Juwon , Kang, Yujin , Watanabe, Hiroki , Uchihashi, Takayuki , Kim, Seung Joong , Kato, Koichi , Lee, Ja Yil , Song, Ji-Joon

Article Issue Date2019-12 View17

Single-molecule visualization reveals the damage search mechanism for the human NER protein XPC-RAD23B File File

Cheon, Na Young , Kim, Hyun-Suk , Yeo, Jung-Eun , Scharer, Orlando D. , Lee, Ja Yil

Article Issue Date2019-09 View16

Sequence imperfections and base triplet recognition by the Rad51/RecA family of recombinases File

Lee, Ja Yil , Steinfeld, Justin B. , Qi, Zhi , Kwon, YoungHo , Sung, Patrick , Greene, Eric C.

Article Issue Date2017-06 View17

ATP hydrolysis Promotes Duplex DNA Release by the RecA Presynaptic Complex File

Lee, Ja Yil , Qi, Zhi , Greene, Eric C.

Article Issue Date2016-10 View17

Investigation of Protein-DNA Interactions by Using Single-molecule DNA Curtain Techniques File

Lee, Ja Yil

Article Issue Date2016-05 View14

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