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Choi, Jang Hyun (최장현)

Department
School of Life Sciences(생명과학부)
Research Interests
Diabetes, Metabolic Disorders, PPARg, Gene Regulation, Anti-Diabetic Drug
Lab
Lab of Diabetes and Metabolism (LDM)
Website
http://sites.google.com/site/diabetesandmetabolism/
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Issue DateTitleAuthor(s)TypeViewAltmetrics
201807RASAL3 preferentially stimulates GTP hydrolysis of the Rho family small GTPase Rac2Choi, Jang HyunARTICLE21
201806Flightless-I Controls Fat Storage in DrosophilaPark, Jung-Eun; Lee, Eun Ji; Kim, Jung Kwan, et alARTICLE89 Flightless-I Controls Fat Storage in Drosophila
201805Zafirlukast promotes insulin secretion by increasing calcium influx through L-type calcium channelsHwang, Hyeon-Jeong; Park, Kyoung-Su; Choi, Jang Hyun, et alARTICLE15 Zafirlukast promotes insulin secretion by increasing calcium influx through L-type calcium channels
201801Noncanonical agonist PPAR gamma ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapyKhandekar, Melin J.; Banks, Alexander S.; Laznik-Bogoslavski, Dina, et alARTICLE85 Noncanonical agonist PPAR gamma ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy
201710Forebrain-specific ablation of phospholipase C gamma 1 causes manic-like behaviorYang, YR; Jung, JH; Kim, SJ, et alARTICLE304 Forebrain-specific ablation of phospholipase C gamma 1 causes manic-like behavior
201608Mechanistic Elucidation Guided by Covalent Inhibitors for the Development of Anti-diabetic PPARγ LigandsBae, Hwan; Jang, Jun Young; Choi, Sun-Sil, et alARTICLE417 Mechanistic Elucidation Guided by Covalent Inhibitors for the Development of Anti-diabetic PPARγ Ligands
201604PPAR gamma Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose TissueChoi, Sun-sil; Kim, Eun-Sun; Jung, Ji-Eun, et alARTICLE682 PPAR gamma Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose Tissue
201512Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice.Yang, Yong Ryoul; Jang, Hyun-Jun; Choi, Sun-Sil, et alARTICLE429 Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice.
201509Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivityChoi, Sunsil; Jung, Ji-Eun; Yang, Yong Ryoul, et alARTICLE487 Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivity
201505Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signalingSuh, Pann-Ghill; Yang, Yong Ryoul; Kim, Dae Hyun, et alARTICLE589
201503Flightless-1, a novel transcriptional modulator of PPARγ through competing with RXRαChoi, Jin Sil; Choi, Sun-Sil; Kim, Eun Sun, et alARTICLE622 Flightless-1, a novel transcriptional modulator of PPARγ through competing with RXRα
201411Revisiting PPAR gamma as a target for the treatment of metabolic disordersChoi, Jang Hyun; Park, Jiyoung; Choi, Sun-SilARTICLE611 Revisiting PPAR gamma as a target for the treatment of metabolic disorders
201411Thrap3 docks on phosphoserine 273 of PPAR gamma and controls diabetic gene programmingChoi, Jang Hyun; Choi, Sun-Sil; Kim, Eun Sun, et alARTICLE517 Thrap3 docks on phosphoserine 273 of PPAR gamma and controls diabetic gene programming
201409A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivityChoi, Sun-Sil; Kim, Eun Sun; Koh, Minseob, et alARTICLE498 A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity
201407OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ miceYang, Yongryoul; Jang H.J.; Yoon, Sunyoung, et alARTICLE504 OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ mice
201405Phenotypic screening to identify small-molecule enhancers for glucose uptake: Target identification and rational optimization of their efficacyKoh, Minseob; Park, Jongmin; Koo, Ja Young, et alARTICLE428 Phenotypic screening to identify small-molecule enhancers for glucose uptake: Target identification and rational optimization of their efficacy
201304C1-Ten Is a Protein Tyrosine Phosphatase of Insulin Receptor Substrate 1 (IRS-1), Regulating IRS-1 Stability and Muscle AtrophyKoh, Ara; Lee, Mi Nam; Yang, Yong Ryoul, et alARTICLE479 C1-Ten Is a Protein Tyrosine Phosphatase of Insulin Receptor Substrate 1 (IRS-1), Regulating IRS-1 Stability and Muscle Atrophy
201301Phospholipase C-gamma 1 involved in brain disordersJang, Hyun-Jun; Yang, Yong Ryoul; Kim, Jung Kuk, et alARTICLE490 Phospholipase C-gamma 1 involved in brain disorders
201211B-cell translocation gene-2 increases hepatic gluconeogenesis via induction of CREBHwang, Seung-Lark; Kwon, Okyun; Lee, Soo Jin, et alARTICLE611 B-cell translocation gene-2 increases hepatic gluconeogenesis via induction of CREB
201208Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exerciseMoon, Hyo Youl; Kim, Se Hyun; Yang, Yong Ryoul, et alARTICLE436 Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise

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