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Choi, Jang Hyun (최장현)

Department
School of Life Sciences(생명과학부)
Research Interests
Diabetes, Metabolic Disorders, PPARg, Gene Regulation, Anti-Diabetic Drug
Lab
Lab of Diabetes and Metabolism (LDM)
Website
http://sites.google.com/site/diabetesandmetabolism/
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Issue DateTitleAuthor(s)TypeViewAltmetrics
201810The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasomemediated degradation of PPAR gammaLee, Jae Min; Choi, Sun Sil; Lee, Yo Han, et alARTICLE86 The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasomemediated degradation of PPAR gamma
201809COL6A3-derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver diseaseLee, Changu; Kim, Min; Lee, Jun Ho, et alARTICLE64 COL6A3-derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease
201807RASAL3 preferentially stimulates GTP hydrolysis of the Rho family small GTPase Rac2Choi, Jang HyunARTICLE62 RASAL3 preferentially stimulates GTP hydrolysis of the Rho family small GTPase Rac2
201806Flightless-I Controls Fat Storage in DrosophilaPark, Jung-Eun; Lee, Eun Ji; Kim, Jung Kwan, et alARTICLE136 Flightless-I Controls Fat Storage in Drosophila
201805Zafirlukast promotes insulin secretion by increasing calcium influx through L-type calcium channelsHwang, Hyeon-Jeong; Park, Kyoung-Su; Choi, Jang Hyun, et alARTICLE70 Zafirlukast promotes insulin secretion by increasing calcium influx through L-type calcium channels
201801Noncanonical agonist PPAR gamma ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapyKhandekar, Melin J.; Banks, Alexander S.; Laznik-Bogoslavski, Dina, et alARTICLE121 Noncanonical agonist PPAR gamma ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy
201710Forebrain-specific ablation of phospholipase C gamma 1 causes manic-like behaviorYang, YR; Jung, JH; Kim, SJ, et alARTICLE358 Forebrain-specific ablation of phospholipase C gamma 1 causes manic-like behavior
201608Mechanistic Elucidation Guided by Covalent Inhibitors for the Development of Anti-diabetic PPARγ LigandsBae, Hwan; Jang, Jun Young; Choi, Sun-Sil, et alARTICLE509 Mechanistic Elucidation Guided by Covalent Inhibitors for the Development of Anti-diabetic PPARγ Ligands
201604PPAR gamma Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose TissueChoi, Sun-sil; Kim, Eun-Sun; Jung, Ji-Eun, et alARTICLE739 PPAR gamma Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose Tissue
201512Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice.Yang, Yong Ryoul; Jang, Hyun-Jun; Choi, Sun-Sil, et alARTICLE473 Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice.
201509Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivityChoi, Sunsil; Jung, Ji-Eun; Yang, Yong Ryoul, et alARTICLE538 Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivity
201505Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signalingSuh, Pann-Ghill; Yang, Yong Ryoul; Kim, Dae Hyun, et alARTICLE628
201503Flightless-1, a novel transcriptional modulator of PPARγ through competing with RXRαChoi, Jin Sil; Choi, Sun-Sil; Kim, Eun Sun, et alARTICLE668 Flightless-1, a novel transcriptional modulator of PPARγ through competing with RXRα
201411Revisiting PPAR gamma as a target for the treatment of metabolic disordersChoi, Jang Hyun; Park, Jiyoung; Choi, Sun-SilARTICLE652 Revisiting PPAR gamma as a target for the treatment of metabolic disorders
201411Thrap3 docks on phosphoserine 273 of PPAR gamma and controls diabetic gene programmingChoi, Jang Hyun; Choi, Sun-Sil; Kim, Eun Sun, et alARTICLE552 Thrap3 docks on phosphoserine 273 of PPAR gamma and controls diabetic gene programming
201409A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivityChoi, Sun-Sil; Kim, Eun Sun; Koh, Minseob, et alARTICLE543 A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity
201407OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ miceYang, Yongryoul; Jang H.J.; Yoon, Sunyoung, et alARTICLE533 OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ mice
201405Phenotypic screening to identify small-molecule enhancers for glucose uptake: Target identification and rational optimization of their efficacyKoh, Minseob; Park, Jongmin; Koo, Ja Young, et alARTICLE464 Phenotypic screening to identify small-molecule enhancers for glucose uptake: Target identification and rational optimization of their efficacy
201304C1-Ten Is a Protein Tyrosine Phosphatase of Insulin Receptor Substrate 1 (IRS-1), Regulating IRS-1 Stability and Muscle AtrophyKoh, Ara; Lee, Mi Nam; Yang, Yong Ryoul, et alARTICLE516 C1-Ten Is a Protein Tyrosine Phosphatase of Insulin Receptor Substrate 1 (IRS-1), Regulating IRS-1 Stability and Muscle Atrophy
201301Phospholipase C-gamma 1 involved in brain disordersJang, Hyun-Jun; Yang, Yong Ryoul; Kim, Jung Kuk, et alARTICLE524 Phospholipase C-gamma 1 involved in brain disorders

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