There are no files associated with this item.
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 5421 | - |
dc.citation.startPage | 5415 | - |
dc.citation.title | ANALYST | - |
dc.citation.volume | 139 | - |
dc.contributor.author | Singh, Renu | - |
dc.contributor.author | Sharma, Abhinav | - |
dc.contributor.author | Hong, Seongkyeol | - |
dc.contributor.author | Jang, Jaesung | - |
dc.date.accessioned | 2023-12-22T02:07:24Z | - |
dc.date.available | 2023-12-22T02:07:24Z | - |
dc.date.created | 2014-10-14 | - |
dc.date.issued | 2014-11 | - |
dc.description.abstract | The influenza virus has received extensive attention due to the recent H1N1 pandemics originating from swine. This study reports a label-free, highly sensitive, and selective electrical immunosensor for the detection of influenza virus H1N1 based on dielectrophoretically deposited single-walled carbon nanotubes (SWCNTs). COOH-functionalized SWCNTs were deposited on a self-assembled monolayer of polyelectrolyte polydiallyldimethyl-ammonium chloride (PDDA) between two gold electrodes by dielectrophoretic and electrostatic forces, which resulted in reproducible, uniform, aligned, and aggregation-free SWCNT channels (2-10 μm in length). Avidin was immobilized onto the PDDA-SWCNT channels, and viral antibodies were immobilized using biotin-avidin coupling. The resistance of the channels increased with the binding of the influenza viruses to the antibodies. These immunosensors showed linear behavior as the virus concentration was varied from 1 to 104 PFU ml−1 along with a detection time of 30 min. The immunosensors with a 2 μm channel length detected 1 PFU ml−1 of the influenza virus accurately (R2 = 0.99) and selectively from MS2 bacteriophages. These immunosensors have the potential to become an important component of a point-of-care test kit that will enable a rapid clinical diagnosis. | - |
dc.identifier.bibliographicCitation | ANALYST, v.139, pp.5415 - 5421 | - |
dc.identifier.doi | 10.1039/c4an01335b | - |
dc.identifier.issn | 0003-2654 | - |
dc.identifier.scopusid | 2-s2.0-84908321166 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/8681 | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84908321166 | - |
dc.identifier.wosid | 000343003700015 | - |
dc.language | 영어 | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Electrical immunosensor based on dielectrophoretically-deposited carbon nanotubes for detection of influenza virus H1N1 | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Tel : 052-217-1404 / Email : scholarworks@unist.ac.kr
Copyright (c) 2023 by UNIST LIBRARY. All rights reserved.
ScholarWorks@UNIST was established as an OAK Project for the National Library of Korea.