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DC Field | Value | Language |
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dc.citation.endPage | 450 | - |
dc.citation.number | 6879 | - |
dc.citation.startPage | 447 | - |
dc.citation.title | NATURE | - |
dc.citation.volume | 416 | - |
dc.contributor.author | Kim, MC | - |
dc.contributor.author | Panstruga, R | - |
dc.contributor.author | Elliott, C | - |
dc.contributor.author | Muller, J | - |
dc.contributor.author | Devoto, A | - |
dc.contributor.author | Yoon, HW | - |
dc.contributor.author | Park, HC | - |
dc.contributor.author | Cho, Moo Je | - |
dc.contributor.author | Schulze-Lefert, P | - |
dc.date.accessioned | 2023-12-22T11:39:18Z | - |
dc.date.available | 2023-12-22T11:39:18Z | - |
dc.date.created | 2014-09-23 | - |
dc.date.issued | 2002-03 | - |
dc.description.abstract | In plants, defence against specific isolates of a pathogen can be triggered by the presence of a corresponding race-specific resistance gene, whereas resistance of a more broad-spectrum nature can result from recessive, presumably loss-of-regulatory-function, mutations. An example of the latter are mlo mutations in barley, which have been successful in agriculture for the control of powdery mildew fungus (Blumeria graminis f. sp. hordei; Bgh). MLO protein resides in the plasma membrane, has seven transmembrane domains, and is the prototype of a sequence-diversified family unique to plants, reminiscent of the seven-transmembrane receptors in fungi and animals. In animals, these are known as G-protein- coupled receptors and exist in three main families, lacking sequence similarity, that are thought to be an example of molecular convergence. MLO seems to function independently of heterotrimeric G proteins. We have identified a domain in MLO that mediates a Ca2+-dependent interaction with calmodulin in vitro. Loss of calmodulin binding halves the ability of MLO to negatively regulate defence against powdery mildew in vivo. We propose a sensor role for MLO in the modulation of defence reactions. | - |
dc.identifier.bibliographicCitation | NATURE, v.416, no.6879, pp.447 - 450 | - |
dc.identifier.doi | 10.1038/416447a | - |
dc.identifier.issn | 0028-0836 | - |
dc.identifier.scopusid | 2-s2.0-0037187626 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/6286 | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0037187626 | - |
dc.identifier.wosid | 000174607800051 | - |
dc.language | 영어 | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.title | Calmodulin interacts with MLO protein to regulate defence against mildew in barley | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scopus | - |
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