There are no files associated with this item.
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 27 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 20 | - |
dc.citation.title | JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | - |
dc.citation.volume | 207 | - |
dc.contributor.author | Jeon, Ki. Seok | - |
dc.contributor.author | Park, Jae Sook | - |
dc.contributor.author | Suh, Yung Doug | - |
dc.contributor.author | Yoon, Minjoong | - |
dc.date.accessioned | 2023-12-22T07:39:29Z | - |
dc.date.available | 2023-12-22T07:39:29Z | - |
dc.date.created | 2022-01-24 | - |
dc.date.issued | 2009-09 | - |
dc.description.abstract | The Raman and fluorescence spectroscopic properties of water-soluble oxo-titanium (IV) meso-tetrakis (1-methyl pyridium-4-yl) porphyrin (O=Ti(TMPyP)(4+)) bound with calf thymus DNA and artificial DNAs such as double stranded poly[d(A-T)(2)] and poly[d(G-C)(2)] have been investigated on the single DNA molecule basis by atomic force microscopy (AFM)-correlated confocal scanning microscope (CSM)-coupled Raman and fluorescence spectroscopic techniques as well as the ensemble-averaged spectroscopy. The ensemble-averaged spectroscopic studies imply that the porphyrin interacts with DNA in different groove binding patterns depending on the base pairs. AFM-images of the different DNAs bound with O=Ti(TMPyP)(4+) were measured, and their morphologies are found to depend on kind of base pairs interacting with O=Ti(TMPyP)(4+). Being correlated with the AFM images, the CSM-coupled Raman and fluorescence spectral properties of the three different single O=Ti(TMPyP)(4+)-DNA complexes were observed to be highly resolved and sensitive to base pair-dependent axial ligation of Ti-O bond as compared to the corresponding ensemble-averaged spectral properties, which affect the groove binding and its strength of the O=Ti(TMPyP)(4+) with DNA. The axial ligation was found to be accompanied by vibration structural change of the porphyrin ring. leading to keep the shape of double stranded poly[d(A-T)(2)] rigid while poly[d(G-C)(2)] and calf thymus DNA flexible after binding with the oxo-titanyl porphyrin. The base pair dependence of the fluorescence decay times of the DNA-bound porphyrins was also observed, implying that an excited-state charge transfer takes place in the G-C rich major groove in calf thymus DNA. These results suggest that binding of O=Ti(TMPyP)(4+) is more preferential with the G-C rich major groove than with the A-T rich minor groove in calf thymus DNA so that the morphology of DNA is changed. (C) 2009 Elsevier B.V. All rights reserved. | - |
dc.identifier.bibliographicCitation | JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, v.207, no.1, pp.20 - 27 | - |
dc.identifier.doi | 10.1016/j.jphotochem.2009.01.005 | - |
dc.identifier.issn | 1010-6030 | - |
dc.identifier.scopusid | 2-s2.0-69649099895 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/58779 | - |
dc.identifier.wosid | 000270625100005 | - |
dc.language | 영어 | - |
dc.publisher | ELSEVIER SCIENCE SA | - |
dc.title | AFM-correlated CSM-coupled Raman and fluorescence properties of water-soluble oxo-titanium (IV) porphyrin bound with DNA | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | Atomic force microscopy (AFM) | - |
dc.subject.keywordAuthor | Confocal scanning microscopy (CSM) | - |
dc.subject.keywordAuthor | Raman/fluorescence spectroscopy | - |
dc.subject.keywordAuthor | DNA-porphyrin interaction | - |
dc.subject.keywordAuthor | Oxo-titanylporphyrin | - |
dc.subject.keywordAuthor | Single DNA | - |
dc.subject.keywordAuthor | Morphology | - |
dc.subject.keywordAuthor | Excited-state charge transfer | - |
dc.subject.keywordAuthor | Base pair dependence | - |
dc.subject.keywordPlus | COMPLEXES | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | TETRAPHENYLPORPHINESULFONATE | - |
dc.subject.keywordPlus | STEREOCHEMISTRY | - |
dc.subject.keywordPlus | INTERCALATION | - |
dc.subject.keywordPlus | SPECTROSCOPY | - |
dc.subject.keywordPlus | FREQUENCY | - |
dc.subject.keywordPlus | SPECTRA | - |
dc.subject.keywordPlus | LIGAND | - |
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Tel : 052-217-1404 / Email : scholarworks@unist.ac.kr
Copyright (c) 2023 by UNIST LIBRARY. All rights reserved.
ScholarWorks@UNIST was established as an OAK Project for the National Library of Korea.