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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 1099 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1083 | - |
dc.citation.title | TRENDS IN IMMUNOLOGY | - |
dc.citation.volume | 41 | - |
dc.contributor.author | Lee, SangJoon | - |
dc.contributor.author | Channappanavar, Rudragouda | - |
dc.contributor.author | Kanneganti, Thirumala-Devi | - |
dc.date.accessioned | 2023-12-21T16:37:21Z | - |
dc.date.available | 2023-12-21T16:37:21Z | - |
dc.date.created | 2022-03-08 | - |
dc.date.issued | 2020-12 | - |
dc.description.abstract | The innate immune system acts as the first line of defense against pathogens, including coronaviruses (CoVs). Severe acute respiratory syndrome (SARS)CoV and Middle East respiratory syndrome (MERS)-CoV are epidemic zoonotic CoVs that emerged at the beginning of the 21st century. The recently emerged virus SARS-CoV-2 is a novel strain of CoV that has caused the coronavirus 2019 (COVID-19) pandemic. Scientific advancements made by studying the SARS-CoV and MERS-CoV outbreaks have provided a foundation for understanding pathogenesis and innate immunity against SARS-CoV-2. In this review, we focus on our present understanding of innate immune responses, inflammasome activation, inflammatory cell death pathways, and cytokine secretion during SARS-CoV, MERS-CoV, and SARS-CoV-2 infection. We also discuss how the pathogenesis of these viruses influences these biological processes. | - |
dc.identifier.bibliographicCitation | TRENDS IN IMMUNOLOGY, v.41, no.12, pp.1083 - 1099 | - |
dc.identifier.doi | 10.1016/j.it.2020.10.005 | - |
dc.identifier.issn | 1471-4906 | - |
dc.identifier.scopusid | 2-s2.0-85095797323 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/57788 | - |
dc.identifier.wosid | 000598634100007 | - |
dc.language | 영어 | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.title | Coronaviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalResearchArea | Immunology | - |
dc.type.docType | Review | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | RESPIRATORY SYNDROME CORONAVIRUS | - |
dc.subject.keywordPlus | MOUSE HEPATITIS-VIRUS | - |
dc.subject.keywordPlus | 2019 COVID-19 INFECTIONS | - |
dc.subject.keywordPlus | I INTERFERON | - |
dc.subject.keywordPlus | RIG-I | - |
dc.subject.keywordPlus | SARS | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | NLRP3 | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | APOPTOSIS | - |
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