A rapid micro polymerase chain reaction system (GenSpector (R) micro PCR) for Hepatitis B virus DNA detection

Abstract

This paper presents a rapid micro PCR (polymerase chain reaction) system (GenSpector (R) Micro PCR) for the application of Hepatitis B virus (HBV) DNA detection. Silicon micromachining technology has been utilized to miniaturize the conventional PCR system. Each module in the system has been installed with an optic system that makes real time in-situ monitoring possible, as well as a built in computer system complete with user-friendly touch screen access. In addition, newly developed electronic temperature controls have cut down response time, making the system faster than ever before. Also, the system enables one or more operators to apply for qualitative or quantitative PCR. Thus, the GenSpector (R) Micro PCR system will have various applications in nucleic acid point-of-care-tests.