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Author

Kwon, H. Moo
Inflammation and Kidney Disorder Lab
Research Interests
  • TonEBP, Obesity, Cancer, Chronic inflammatory diseases, Brain disorder, Kidney disorders, Genomic instability

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Transcriptional activator tone-binding protein in cellular protection and differentiation

Cited 6 times inthomson ciCited 5 times inthomson ci
Title
Transcriptional activator tone-binding protein in cellular protection and differentiation
Author
Kim, Jeong AhJeon, Un SilKwon, Min SeongLim, Sun WooKwon, H. Moo
Keywords
TONICITY-INDUCED EXPRESSION;  STIMULATES TRANSCRIPTION;  SYSTEMIC HYPERTONICITY;  OSMOPROTECTIVE GENES;  ESSENTIAL REGULATOR;  RAT-BRAIN;  TONEBP/NFAT5;  KIDNEY;  CELLS;  NFAT5
Issue Date
2007
Publisher
ELSEVIER ACADEMIC PRESS INC
Citation
OSMOSENSING AND OSMOSIGNALING, v.428, no., pp.253 - 267
Abstract
The TonE-binding protein (TonEBP) is a transcriptional activator in the Rel family that includes NF kappa B and NFAT. TonEBP is critical for the development and function of the renal medulla, which is a major regulator of water homeostasis. TonEBP is also implicated in diabetic nephropathy and inflammation. Established methods for biochemical and histochemical detection and functional analysis of TonEBP, including identification of novel TonEBP target genes, are described for those who are interested in investigating function and regulation of TonEBP.
URI
http://scholarworks.unist.ac.kr/handle/201301/4890
DOI
http://dx.doi.org/10.1016/S0076-6879(07)28014-0
ISSN
0076-6879
Appears in Collections:
SLS_Journal Papers
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