Biosensors for pathogen detection: A smart approach towards clinical diagnosis

Abstract

The present review concerns the recent developments of nucleic acid biosensors for detection of the human pathogens as infectious diseases management at an early stage is currently of prime interest so as to circumvent the delay in diagnosis, side effects of drugs and unnecessary health hazards. The advantages of biosensors over existing detection methodologies and the role of various immobilization matrices used for fabrication of nucleic acid sensors are discussed. Besides this, efforts have been made to discuss the various techniques used for biosensor construction, the analytical performance of these biodevices for the bacterial and viral pathogens for their applications to medical diagnosis.