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- Shin, Heungjoo
- Micro/Nano Integrated Systems Lab.
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NANOGAP ELECTRICAL DETECTION OF SINGLE MOLECULES TRANSLOCATING THROUGH A NANOCHANNEL WITH TRANSVERSE NANOELECTRODES AND FUNNELS POPULATED WITH AN ARRAY OF NANOPILLARS
- Author(s)
- Shin, Heungjoo, Uba, FI, Wu, J, Park, S, Moldova, D, Novak, B, Park, DK, Cho, YK, Kim, T, Soper, SA
- Issued Date
- 2011-10-02
- Citation
- 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, pp.401 - 403
- Abstract
- We are developing techniques for the fabrication of mixed-scale systems (nm to mm) used for the molecular-scale sensing of single-molecules (DNAs, RNAs, peptides and proteins). The system consists of microchannels and nanochannels (10-100 nm) with integrated electrodes of similar dimensions for transducing single molecules. The system is applicable for the rapid and efficient sequencing of biopolymers by measuring flight-times of monomer units clipped from a single polymer. Preliminary results from calculations and Molecular Dynamic (MD) simulations have supported the viability of our system.
- Publisher
- 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
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