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Author

Takayama, Shuichi
Cell and Microfluidics Lab
Research Interests
  • Bio-MEMS and Microfluidics

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Microfluidic Automation Using Elastomeric Valves and Droplets: Reducing Reliance on External Controllers

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Title
Microfluidic Automation Using Elastomeric Valves and Droplets: Reducing Reliance on External Controllers
Author
Kim, Sung-JinLai, DavidPark, Joong YullYokokawa, RyujiTakayama, Shuichi
Keywords
Bio-chemical applications; Control fluids; Droplet-based microfluidics; External control; External controller; External pressures; Gain insight; High-throughput analysis; Micro droplets; Micro-fluidic devices; Microfluidic circuit; Microfluidic valves; Physical limitations; Working principles
Issue Date
201210
Publisher
WILEY-V C H VERLAG GMBH
Citation
SMALL, v.8, no.19, pp.2925 - 2934
Abstract
This paper gives an overview of elastomeric valve- and droplet-based microfluidic systems designed to minimize the need of external pressure to control fluid flow. This Concept article introduces the working principle of representative components in these devices along with relevant biochemical applications. This is followed by providing a perspective on the roles of different microfluidic valves and systems through comparison of their similarities and differences with transistors (valves) and systems in microelectronics. Despite some physical limitation of drawing analogies from electronic circuits, automated microfluidic circuit design can gain insights from electronic circuits to minimize external control units, while implementing high-complexity and high-throughput analysis.
URI
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DOI
http://dx.doi.org/10.1002/smll.201200456
ISSN
1613-6810
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