Large-Scale, Ultrapliable, and Free-Standing Nanomembranes
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- Large-Scale, Ultrapliable, and Free-Standing Nanomembranes
- Kang, Edward; Ryoo, Jihee; Jeong, Gi Seok; Choi, Yoon Young; Jeong, Seung Min; Ju, Jongil; Chung, Seok; Takayama, Shuichi; Lee, Sang-Hoon
- Cell monolayers; Epithelial monolayers; Free-standing nanomembranes; Nanomembranes; PDMS membrane; Tight junctions; Ultra-thin; Ultra-thin membranes
- Issue Date
- WILEY-V C H VERLAG GMBH
- ADVANCED MATERIALS, v.25, no.15, pp.2167 - 2173
- The creation and characterization of large-area ultrathin highly pliable free-standing PDMS membranes and their application to the study of cellular epithelia is described. The ultra-thin membranes permitted the straight forward calculation of cell monolayer moduli, derived from measured stress-strain curves. These measurements allowed the unprecedented detection of cellular-level injury in the epithelia caused by the rupture of cell-cell tight junctions in response to stretching.
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