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Author

Cho, Hyungjoon
Biomedical Imaging Science and Engineering Lab(BISE)
Research Interests
  • Imaging tumor microenvironments, susceptibility contrast based MR structural imaging, ultra fast acquisitions of dynamic MR, algorithm/Hardware development for magnetic particle imaging

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Magnetic field anisotropy based MR tractography

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Title
Magnetic field anisotropy based MR tractography
Author
Han, S. H.Song, Y. K.Cho, F. H.Ryu, S.Cho, G.Song, Y. -Q.Cho, Hyungjoon
Keywords
Anisotropic structure; Capillary model; Diffusion anisotropy; External magnetic field; Fiber materials; Fiber structures; Interference patterns; Internal gradient; Magnetic field strengths; MR tractography; Noninvasive measurements; Structural orientations; Tractography; Vessel orientation imaging; Water diffusion
Issue Date
201110
Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
Citation
JOURNAL OF MAGNETIC RESONANCE, v.212, no.2, pp.386 - 393
Abstract
Non-invasive measurements of structural orientation provide unique information regarding the connectivity and functionality of fiber materials. In the present study, we use a capillary model to demonstrate that the direction of fiber structure can be obtained from susceptibility-induced magnetic field anisotropy. The interference pattern between internal and external magnetic field gradients carries the signature of the underlying anisotropic structure and can be measured by MRI-based water diffusion measurements. Through both numerical simulation and experiments, we found that this technique can determine the capillary orientation within 3. Therefore, susceptibility-induced magnetic field anisotropy may be useful for an alternative tractography method when diffusion anisotropy is small at higher magnetic field strength without the need to rotate the subject inside the scanner.
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DOI
http://dx.doi.org/10.1016/j.jmr.2011.07.021
ISSN
1090-7807
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