Full metadata record
DC Field | Value | Language |
---|---|---|
dc.citation.number | 14 | - |
dc.citation.startPage | 3057 | - |
dc.citation.title | MATERIALS | - |
dc.citation.volume | 13 | - |
dc.contributor.author | Cao, Shuaishuai | - |
dc.contributor.author | Han, Jonghyeuk | - |
dc.contributor.author | Sharma, Neha | - |
dc.contributor.author | Msallem, Bilal | - |
dc.contributor.author | Jeong, Wonwoo | - |
dc.contributor.author | Son, Jeonghyun | - |
dc.contributor.author | Kunz, Christoph | - |
dc.contributor.author | Kang, Hyun-Wook | - |
dc.contributor.author | Thieringer, Florian M. | - |
dc.date.accessioned | 2023-12-21T17:15:45Z | - |
dc.date.available | 2023-12-21T17:15:45Z | - |
dc.date.created | 2020-07-06 | - |
dc.date.issued | 2020-07 | - |
dc.description.abstract | 3D printed biomaterials have been extensively investigated and developed in the field of bone regeneration related to clinical issues. However, specific applications of 3D printed biomaterials in different dental areas have seldom been reported. In this study, we aimed to and successfully fabricated 3D poly (lactic-co-glycolic acid)/beta-tricalcium phosphate (3D-PLGA/TCP) and 3D beta-tricalcium phosphate (3D-TCP) scaffolds using two relatively distinct 3D printing (3DP) technologies. Conjunctively, we compared and investigated mechanical and biological responses on human dental pulp stem cells (hDPSCs). Physicochemical properties of the scaffolds, including pore structure, chemical elements, and compression modulus, were characterized. hDPSCs were cultured on scaffolds for subsequent investigations of biocompatibility and osteoconductivity. Our findings indicate that 3D printed PLGA/TCP and beta-tricalcium phosphate (beta-TCP) scaffolds possessed a highly interconnected and porous structure. 3D-TCP scaffolds exhibited better compressive strength than 3D-PLGA/TCP scaffolds, while the 3D-PLGA/TCP scaffolds revealed a flexible mechanical performance. The introduction of 3D structure and beta-TCP components increased the adhesion and proliferation of hDPSCs and promoted osteogenic differentiation. In conclusion, 3D-PLGA/TCP and 3D-TCP scaffolds, with the incorporation of hDPSCs as a personalized restoration approach, has a prospective potential to repair minor and critical bone defects in oral and maxillofacial surgery, respectively. | - |
dc.identifier.bibliographicCitation | MATERIALS, v.13, no.14, pp.3057 | - |
dc.identifier.doi | 10.3390/ma13143057 | - |
dc.identifier.issn | 1996-1944 | - |
dc.identifier.scopusid | 2-s2.0-85088507007 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/32973 | - |
dc.identifier.url | https://www.mdpi.com/1996-1944/13/14/3057 | - |
dc.identifier.wosid | 000554119200001 | - |
dc.language | 영어 | - |
dc.publisher | MDPI | - |
dc.title | In Vitro Mechanical and Biological Properties of 3D Printed Polymer Composite and β-tricalcium Phosphate Scaffold on Human Dental Pulp Stem Cells | - |
dc.type | Article | - |
dc.description.isOpenAccess | TRUE | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | 3D printing | - |
dc.subject.keywordAuthor | dental biomaterials | - |
dc.subject.keywordAuthor | polymer printing | - |
dc.subject.keywordAuthor | ceramic printing | - |
dc.subject.keywordAuthor | human dental pulp stem cell | - |
dc.subject.keywordAuthor | in vitro research | - |
dc.subject.keywordAuthor | bone regeneration | - |
dc.subject.keywordPlus | OSTEOGENIC DIFFERENTIATION | - |
dc.subject.keywordPlus | BONE REGENERATION | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordPlus | ENHANCEMENT | - |
dc.subject.keywordPlus | HYDROXYAPATITE | - |
dc.subject.keywordPlus | RECONSTRUCTION | - |
dc.subject.keywordPlus | DEFECT | - |
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Tel : 052-217-1404 / Email : scholarworks@unist.ac.kr
Copyright (c) 2023 by UNIST LIBRARY. All rights reserved.
ScholarWorks@UNIST was established as an OAK Project for the National Library of Korea.