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Choi, Jang Hyun
Lab of Diabetes and Metabolism Lab.
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dc.citation.endPage 62 -
dc.citation.number 1 -
dc.citation.startPage 51 -
dc.citation.title ADVANCES IN BIOLOGICAL REGULATION -
dc.citation.volume 53 -
dc.contributor.author Jang, Hyun-Jun -
dc.contributor.author Yang, Yong Ryoul -
dc.contributor.author Kim, Jung Kuk -
dc.contributor.author Choi, Jang Hyun -
dc.contributor.author Seo, Young-Kyo -
dc.contributor.author Lee, Yong Hwa -
dc.contributor.author Lee, Jeung Eun -
dc.contributor.author Ryu, Sung Ho -
dc.contributor.author Suh, Pann-Ghill -
dc.date.accessioned 2023-12-22T04:16:05Z -
dc.date.available 2023-12-22T04:16:05Z -
dc.date.created 2013-07-02 -
dc.date.issued 2013-01 -
dc.description.abstract Phosphoinositide-specific phospholipase C-γ1 (PLC-γ1) is an important signaling regulator involved in various cellular processes. In brain, PLC-γ1 is highly expressed and participates in neuronal cell functions mediated by neurotrophins. Consistent with essential roles of PLC-γ1, it is involved in development of brain and synaptic transmission. Significantly, abnormal expression and activation of PLC-γ1 appears in various brain disorders such as epilepsy, depression, Huntington's disease and Alzheimer's disease. Thus, PLC-γ1 has been implicated in brain functions as well as related brain disorders. In this review, we discuss the roles of PLC-γ1 in neuronal functions and its pathological relevance to diverse brain diseases. -
dc.identifier.bibliographicCitation ADVANCES IN BIOLOGICAL REGULATION, v.53, no.1, pp.51 - 62 -
dc.identifier.doi 10.1016/j.jbior.2012.09.008 -
dc.identifier.issn 2212-4926 -
dc.identifier.scopusid 2-s2.0-84874001481 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/3168 -
dc.language 영어 -
dc.publisher ELSEVIER -
dc.title Phospholipase C-gamma 1 involved in brain disorders -
dc.type Article -
dc.description.journalRegisteredClass scopus -

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