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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 62 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 51 | - |
dc.citation.title | ADVANCES IN BIOLOGICAL REGULATION | - |
dc.citation.volume | 53 | - |
dc.contributor.author | Jang, Hyun-Jun | - |
dc.contributor.author | Yang, Yong Ryoul | - |
dc.contributor.author | Kim, Jung Kuk | - |
dc.contributor.author | Choi, Jang Hyun | - |
dc.contributor.author | Seo, Young-Kyo | - |
dc.contributor.author | Lee, Yong Hwa | - |
dc.contributor.author | Lee, Jeung Eun | - |
dc.contributor.author | Ryu, Sung Ho | - |
dc.contributor.author | Suh, Pann-Ghill | - |
dc.date.accessioned | 2023-12-22T04:16:05Z | - |
dc.date.available | 2023-12-22T04:16:05Z | - |
dc.date.created | 2013-07-02 | - |
dc.date.issued | 2013-01 | - |
dc.description.abstract | Phosphoinositide-specific phospholipase C-γ1 (PLC-γ1) is an important signaling regulator involved in various cellular processes. In brain, PLC-γ1 is highly expressed and participates in neuronal cell functions mediated by neurotrophins. Consistent with essential roles of PLC-γ1, it is involved in development of brain and synaptic transmission. Significantly, abnormal expression and activation of PLC-γ1 appears in various brain disorders such as epilepsy, depression, Huntington's disease and Alzheimer's disease. Thus, PLC-γ1 has been implicated in brain functions as well as related brain disorders. In this review, we discuss the roles of PLC-γ1 in neuronal functions and its pathological relevance to diverse brain diseases. | - |
dc.identifier.bibliographicCitation | ADVANCES IN BIOLOGICAL REGULATION, v.53, no.1, pp.51 - 62 | - |
dc.identifier.doi | 10.1016/j.jbior.2012.09.008 | - |
dc.identifier.issn | 2212-4926 | - |
dc.identifier.scopusid | 2-s2.0-84874001481 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/3168 | - |
dc.language | 영어 | - |
dc.publisher | ELSEVIER | - |
dc.title | Phospholipase C-gamma 1 involved in brain disorders | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scopus | - |
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