File Download
There are no files associated with this item.
SFX Link
- Find it @ UNIST can give you direct access to the published full text of this article. (UNISTARs only)
- Myung, Kyungjae
- Center for Genomic Integrity
Views & Downloads
Detailed Information
Cited time in 
Cited time in 
Cited time in
Metadata Downloads
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.citation.endPage | U118 | - |
| dc.citation.number | 9 | - |
| dc.citation.startPage | 1032 | - |
| dc.citation.title | NATURE CELL BIOLOGY | - |
| dc.citation.volume | 8 | - |
| dc.contributor.author | De Piccoli, Giacomo | - |
| dc.contributor.author | Cortes-Ledesma, Felipe | - |
| dc.contributor.author | Ira, Gregory | - |
| dc.contributor.author | Torres-Rosell, Jordi | - |
| dc.contributor.author | Uhle, Stefan | - |
| dc.contributor.author | Farmer, Sarah | - |
| dc.contributor.author | Hwang, Ji-Young | - |
| dc.contributor.author | Machin, Felix | - |
| dc.contributor.author | Ceschia, Audrey | - |
| dc.contributor.author | McAleenan, Alexandra | - |
| dc.contributor.author | Cordon-Preciado, Violeta | - |
| dc.contributor.author | Clemente-Blanco, Andres | - |
| dc.contributor.author | Vilella-Mitjana, Felip | - |
| dc.contributor.author | Ullal, Pranav | - |
| dc.contributor.author | Jarmuz, Adam | - |
| dc.contributor.author | Leitao, Beatriz | - |
| dc.contributor.author | Bressan, Debra | - |
| dc.contributor.author | Dotiwala, Farokh | - |
| dc.contributor.author | Papusha, Alma | - |
| dc.contributor.author | Zhao, Xiaolan | - |
| dc.contributor.author | Myung, Kyungjae | - |
| dc.contributor.author | Haber, James E. | - |
| dc.contributor.author | Aguilera, Andres | - |
| dc.contributor.author | Aragon, Luis | - |
| dc.date.accessioned | 2023-12-22T09:42:17Z | - |
| dc.date.available | 2023-12-22T09:42:17Z | - |
| dc.date.created | 2020-01-31 | - |
| dc.date.issued | 2006-09 | - |
| dc.description.abstract | DNA double-strand breaks (DSB) can arise during DNA replication, or after exposure to DNA-damaging agents, and their correct repair is fundamental for cell survival and genomic stability. Here, we show that the Smc5-Smc6 complex is recruited to DSBs de novo to support their repair by homologous recombination between sister chromatids. In addition, we demonstrate that Smc5-Smc6 is necessary to suppress gross chromosomal rearrangements. Our findings show that the Smc5-Smc6 complex is essential for genome stability as it promotes repair of DSBs by error-free sisterchromatid recombination (SCR), thereby suppressing inappropriate non-sister recombination events. | - |
| dc.identifier.bibliographicCitation | NATURE CELL BIOLOGY, v.8, no.9, pp.1032 - U118 | - |
| dc.identifier.doi | 10.1038/ncb1466 | - |
| dc.identifier.issn | 1465-7392 | - |
| dc.identifier.scopusid | 2-s2.0-33748199605 | - |
| dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/31069 | - |
| dc.identifier.url | https://www.nature.com/articles/ncb1466 | - |
| dc.identifier.wosid | 000240241700021 | - |
| dc.language | 영어 | - |
| dc.publisher | NATURE PUBLISHING GROUP | - |
| dc.title | Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination | - |
| dc.type | Article | - |
| dc.description.isOpenAccess | FALSE | - |
| dc.relation.journalWebOfScienceCategory | Cell Biology | - |
| dc.relation.journalResearchArea | Cell Biology | - |
| dc.type.docType | Article | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.subject.keywordPlus | SACCHAROMYCES-CEREVISIAE | - |
| dc.subject.keywordPlus | YEAST | - |
| dc.subject.keywordPlus | COHESIN | - |
| dc.subject.keywordPlus | REGIONS | - |
| dc.subject.keywordPlus | GENES | - |
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.