File Download

There are no files associated with this item.

  • Find it @ UNIST can give you direct access to the published full text of this article. (UNISTARs only)
Related Researcher

조윤경

Cho, Yoon-Kyoung
FRUITS Lab.
Read More

Views & Downloads

Detailed Information

Cited time in webofscience Cited time in scopus
Metadata Downloads

Universal method for direct bioconjugation of electrode surfaces by fast enzymatic polymerization

Author(s)
Kumar, SumitHaque, AI-Monsur JiaulRio, Jonathan Sabate delGautam, ShreedharCho, Yoon-Kyoung
Issued Date
2019-02
DOI
10.1016/j.bios.2018.12.017
URI
https://scholarworks.unist.ac.kr/handle/201301/25642
Fulltext
https://www.sciencedirect.com/science/article/pii/S0956566318309710
Citation
BIOSENSORS & BIOELECTRONICS, v.127, pp.50 - 56
Abstract
We report HRP-catalyzed polymerization of Tannic acid (TA) and application of the poly (Tannic acid) (p(TA)) as a versatile platform for covalent immobilization of biomolecules on various electrode surfaces based on electrochemical oxidation of the p(TA) and subsequent oxidative coupling reactions with the biomolecules. We also used this method for capturing cancer cells through a linker molecule, folic acid (FA). Furthermore, we have demonstrated that enhanced electrocatalytic activity of the p(TA)-modified surface could be used for simultaneous electrochemical determination of biologically important electroactive molecules such as ascorbic acid (AA), dopamine (DA), and uric acid (UA). This HRP-catalyzed polymerization of TA and p(TA)-mediated surface modification method can provide a simple and new framework to construct multifunctional platforms for covalent attachment of biomolecules and development of sensitive electrochemical sensing devices
Publisher
ELSEVIER ADVANCED TECHNOLOGY
ISSN
0956-5663
Keyword (Author)
Electrode modificationBioconjugationTannic acidEnzymatic polymerization
Keyword
DIELS-ALDER REACTIONTANNIC-ACIDCHEMISTRY

qrcode

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.