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DC Field | Value | Language |
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dc.citation.endPage | 408 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 402 | - |
dc.citation.title | JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY | - |
dc.citation.volume | 32 | - |
dc.contributor.author | Kim, Yu-Jin | - |
dc.contributor.author | Oh, You-Kwan | - |
dc.contributor.author | Kang, Whankoo | - |
dc.contributor.author | Lee, Eun Yeol | - |
dc.contributor.author | Park, Sunghoon | - |
dc.date.accessioned | 2023-12-22T10:12:52Z | - |
dc.date.available | 2023-12-22T10:12:52Z | - |
dc.date.created | 2017-03-04 | - |
dc.date.issued | 2005-09 | - |
dc.description.abstract | Caseinomacropeptide is a polypeptide of 64 amino acid residues (106-169) derived from the C-terminal part of the mammalian milk k-casein. This macropeptide has various biological activities and is used as a functional food ingredient as well as a pharmaceutical compound. The gene encoding the human caseinomacropeptide (hCMP) was synthesized and expressed with an alpha-factor secretion signal in the two yeast strains, Saccharomyces cerevisiae and Pichia pastoris. The complete polypeptide of the recombinant hCMP was produced and secreted in a culture medium by both the strains, but the highest production was observed in S. cerevisiae with a galactose-inducible promoter. In a fed-batch bioreactor culture, 2.5 g/l of the recombinant hCMP was obtained from the S. cerevisiae at 97 h. | - |
dc.identifier.bibliographicCitation | JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, v.32, no.9, pp.402 - 408 | - |
dc.identifier.doi | 10.1007/s10295-005-0010-2 | - |
dc.identifier.issn | 1367-5435 | - |
dc.identifier.scopusid | 2-s2.0-28344448370 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/25375 | - |
dc.identifier.url | https://link.springer.com/article/10.1007%2Fs10295-005-0010-2 | - |
dc.identifier.wosid | 000232954700004 | - |
dc.language | 영어 | - |
dc.publisher | SPRINGER HEIDELBERG | - |
dc.title | Production of human caseinomacropeptide in recombinant Saccharomyces cerevisiae and Pichia pastoris | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | caseinomacropeptide | - |
dc.subject.keywordAuthor | recombinant yeast | - |
dc.subject.keywordAuthor | secretion | - |
dc.subject.keywordAuthor | promoter | - |
dc.subject.keywordAuthor | fed-batch | - |
dc.subject.keywordPlus | HUMAN LIPOCORTIN-I | - |
dc.subject.keywordPlus | FEEDING STRATEGY | - |
dc.subject.keywordPlus | GAL10 PROMOTER | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | PURIFICATION | - |
dc.subject.keywordPlus | SEQUENCES | - |
dc.subject.keywordPlus | YEASTS | - |
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