BROWSE

Related Researcher

Author

Choi, Sung-Deuk
Environmental Analytical Chemistry Lab (EACL)
Research Interests
  • Persistent organic pollutants, Environmental Analysis and monitoring, Multimedia modeling

ITEM VIEW & DOWNLOAD

Influence of exposure to perfluoroalkyl substances (PFASs) on the Korean general population: 10-year trend and health effects

Cited 0 times inthomson ciCited 0 times inthomson ci
Title
Influence of exposure to perfluoroalkyl substances (PFASs) on the Korean general population: 10-year trend and health effects
Author
Seo, Sung-HeeSon, Min-HuiChoi, Sung-DeukLee, Duk-HeeChang, Yoon-Seok
Keywords
PFASs; Serum; Temporal trend; Health effects; Korea
Issue Date
201804
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Citation
ENVIRONMENT INTERNATIONAL, v.113, no., pp.149 - 161
Abstract
This study demonstrated the 10-year trend of 13 perfluoroalkyl substances (PFASs) serum levels among 786 adults living in Seoul, Korea. PFAS levels gradually increased from 2006 to 2013, decreasing thereafter. We found that PFAS levels were higher in male than in female participants and were positively correlated with age. PFASs were not significantly correlated with body mass index, although we observed positive correlations with total cholesterol, low-density lipoprotein cholesterol, and triglycerides and negative correlations with high-density lipoprotein cholesterol. Uric acid and free thyroxine (fT4) also showed positive correlations with major congeners while correlations between thyroid stimulating hormone and PFASs were inconsistent. We demonstrated significant correlations between fT4 and perfluorononanoic acid (PFNA), perfluorohexane sulfonate (PFHxS), and perfluorodecanoic acid (PFDA). There were significant differences in PFHxS and perfluorododecanoic acid (PFDoDA) levels between participants with and without diabetes. Furthermore, principal component analysis suggested possible differences in disease manifestation based on the congener distribution of PFASs. This study is the first study of temporal trends of 13 PFAS congeners in serum samples obtained from the Korean general population; it is currently longest and largest scale study of this type.
URI
Go to Link
DOI
http://dx.doi.org/10.1016/j.envint.2018.01.025
ISSN
0160-4120
Appears in Collections:
UEE_Journal Papers

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qr_code

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU