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Park, Jang-Ung
Flexible Nano-electronics & Biotechnology Lab
Research Interests
  • Wireless wearable electronics, flexible electronics, printed electronics, nano-bio interfaces

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Direct diversification of unmasked quinazolin-4(3: H)-ones through orthogonal reactivity modulation

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Title
Direct diversification of unmasked quinazolin-4(3: H)-ones through orthogonal reactivity modulation
Author
Lee, Jae BinKang, Mi EunKim, JooheeLee, Chang YoungKee, Jung-MinMyung, KyungjaePark, Jang-UngHong, Sung You
Issue Date
201709
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.53, no.75, pp.10394 - 10397
Abstract
Here we report a set of direct functionalization methods of unmasked 2-phenylquinazolin-4(3H)-ones, a privileged alkaloid core, without the installation/removal event of protecting groups or exogenous coordinating moieties. Divergent pathways were modulated with transition-metal catalysts by suppressing competitive reactivities, leading to N-arylation, annulative π-extension, or C-H fluorination.
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DOI
http://dx.doi.org/10.1039/c7cc05794f
ISSN
1359-7345
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