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Author

Park, Jung-Hoon
Bio-Optics Lab
Research Interests
  • Biomedical optics, wavefront shaping, In-vivo deep tissue imaging

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Large-field-of-view imaging by multi-pupil adaptive optics

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Title
Large-field-of-view imaging by multi-pupil adaptive optics
Author
Park, Jung-HoonKong, LingjieZhou, YifengCui, Meng
Keywords
Fluorescence imaging; Mouse; Neuroscience; Optical imaging
Issue Date
201706
Publisher
NATURE PUBLISHING GROUP
Citation
NATURE METHODS, v.14, no.6, pp.581 - 583
Abstract
Adaptive optics can correct for optical aberrations. We developed multi-pupil adaptive optics (MPAO), which enables simultaneous wavefront correction over a field of view of 450 × 450 μm2 and expands the correction area to nine times that of conventional methods. MPAO's ability to perform spatially independent wavefront control further enables 3D nonplanar imaging. We applied MPAO to in vivo structural and functional imaging in the mouse brain.
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DOI
http://dx.doi.org/10.1038/nmeth.4290
ISSN
1548-7091
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