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Suh, Pann-Ghill
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dc.citation.endPage 5 -
dc.citation.startPage 1 -
dc.citation.title ADVANCES IN BIOLOGICAL REGULATION -
dc.citation.volume 63 -
dc.contributor.author Ramazzotti, Giulia -
dc.contributor.author Faenza, Irene -
dc.contributor.author Fiume, Roberta -
dc.contributor.author Billi, Anna Maria -
dc.contributor.author Manzoli, Lucia -
dc.contributor.author Mongiorgi, Sara -
dc.contributor.author Ratti, Stefano -
dc.contributor.author McCubrey, James A. -
dc.contributor.author Suh, Pann-Ghill -
dc.contributor.author Cocco, Lucio -
dc.contributor.author Follo, Matilde Y. -
dc.date.accessioned 2023-12-21T22:45:47Z -
dc.date.available 2023-12-21T22:45:47Z -
dc.date.created 2016-12-26 -
dc.date.issued 2017-01 -
dc.description.abstract Phosphoinositide-phospholipase C-β1 (PLC-β1) plays a crucial role in the initiation of the genetic program responsible for muscle differentiation and osteogenesis. During myogenic differentiation of murine C2C12 myoblasts, PLC-β1 signaling pathway involves the Inositol Polyphosphate Multikinase (IPMK) and β-catenin as downstream effectors. By means of c-jun binding to cyclin D3 promoter, the activation of PLC-β1 pathway determines cyclin D3 accumulation. However, osteogenesis requires PLC-β1 expression and up-regulation but it does not affect cyclin D3 levels, suggesting that the two processes require the activation of different mediators. -
dc.identifier.bibliographicCitation ADVANCES IN BIOLOGICAL REGULATION, v.63, pp.1 - 5 -
dc.identifier.doi 10.1016/j.jbior.2016.10.005 -
dc.identifier.issn 2212-4926 -
dc.identifier.scopusid 2-s2.0-85001638618 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/21396 -
dc.identifier.url http://www.sciencedirect.com/science/article/pii/S2212492616300562 -
dc.language 영어 -
dc.publisher ELSEVIER SCI LTD -
dc.title PLC-β1 and cell differentiation: An insight into myogenesis and osteogenesis -
dc.type Article -
dc.description.isOpenAccess FALSE -
dc.description.journalRegisteredClass scopus -

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