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- Scharer, Orlando D.
- Schärer Lab.
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| DC Field | Value | Language |
|---|---|---|
| dc.citation.endPage | 3469 | - |
| dc.citation.number | 14 | - |
| dc.citation.startPage | 3466 | - |
| dc.citation.title | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
| dc.citation.volume | 51 | - |
| dc.contributor.author | Hentschel, Sarah | - |
| dc.contributor.author | Alzeer, Jawad | - |
| dc.contributor.author | Angelov, Todor | - |
| dc.contributor.author | Schaerer, Orlando D. | - |
| dc.contributor.author | Luedtke, Nathan W. | - |
| dc.date.accessioned | 2023-12-22T05:11:45Z | - |
| dc.date.available | 2023-12-22T05:11:45Z | - |
| dc.date.created | 2017-01-26 | - |
| dc.date.issued | 2012-04 | - |
| dc.description.abstract | The missing linking: BCNU is a chemotherapy drug that generates an ethylene bridge between N1 of deoxyguanosine and N3 of deoxycytidine. No synthesis of a DNA containing this moiety has been reported until now. A new strategy uses a photocaged nucleobase that, when released, generates a highly reactive intermediate which cross-links the opposing DNA strand in a manner analogous to BCNU (see scheme, NBOC=ortho-nitrobenzyloxycarbonyl). | - |
| dc.identifier.bibliographicCitation | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.51, no.14, pp.3466 - 3469 | - |
| dc.identifier.doi | 10.1002/anie.201108018 | - |
| dc.identifier.issn | 1433-7851 | - |
| dc.identifier.scopusid | 2-s2.0-84859243628 | - |
| dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/21254 | - |
| dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1002/anie.201108018/abstract | - |
| dc.identifier.wosid | 000302059400035 | - |
| dc.language | 영어 | - |
| dc.publisher | WILEY-V C H VERLAG GMBH | - |
| dc.title | Synthesis of DNA Interstrand Cross-Links Using a Photocaged Nucleobase | - |
| dc.type | Article | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.subject.keywordAuthor | alkylation | - |
| dc.subject.keywordAuthor | DNA | - |
| dc.subject.keywordAuthor | nitrosourea | - |
| dc.subject.keywordAuthor | photocage | - |
| dc.subject.keywordPlus | LIPID-PEROXIDATION | - |
| dc.subject.keywordPlus | CHEMICAL-SYNTHESIS | - |
| dc.subject.keywordPlus | PROTECTING GROUPS | - |
| dc.subject.keywordPlus | DUPLEX DNA | - |
| dc.subject.keywordPlus | REPAIR | - |
| dc.subject.keywordPlus | OLIGONUCLEOTIDES | - |
| dc.subject.keywordPlus | ANALOG | - |
| dc.subject.keywordPlus | ACID | - |
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