dc.citation.startPage |
21 |
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dc.citation.title |
BIOMATERIALS RESEARCH |
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dc.citation.volume |
18 |
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dc.contributor.author |
Moon, Hyojin |
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dc.contributor.author |
Lee, Jisu |
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dc.contributor.author |
Kim, Hansol |
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dc.contributor.author |
Heo, Somin |
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dc.contributor.author |
Min, Junseon |
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dc.contributor.author |
Kang, Sebyung |
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dc.date.accessioned |
2023-12-22T02:06:40Z |
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dc.date.available |
2023-12-22T02:06:40Z |
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dc.date.created |
2016-10-13 |
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dc.date.issued |
2014-11 |
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dc.description.abstract |
Background - Protein cage nanoparticles are promising nanoplatform candidates for efficient delivery systems of diagnostics and/or therapeutics because of their uniform size and structure as well as high biocompatibility and biodegradability. Encapsulin protein cage nanoparticle is used to develop a cell-specific targeting optical nanoprobe. Results - FcBPs are genetically inserted and successfully displayed on the surface of encapsulin to form FcBP-encapsulin. Selectively binding of FcBP-encapsulin to SCC-7 is visualized with fluorescent microscopy. Conclusions - Encapsulin protein cage nanoparticle is robust enough to maintain their structure at high temperature and easily acquires multifunctions on demand through the combination of genetic and chemical modifications. |
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dc.identifier.bibliographicCitation |
BIOMATERIALS RESEARCH, v.18, pp.21 |
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dc.identifier.doi |
10.1186/2055-7124-18-21 |
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dc.identifier.issn |
2055-7124 |
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dc.identifier.scopusid |
2-s2.0-85001159259 |
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dc.identifier.uri |
https://scholarworks.unist.ac.kr/handle/201301/20623 |
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dc.identifier.url |
https://biomaterialsres.biomedcentral.com/articles/10.1186/2055-7124-18-21 |
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dc.language |
영어 |
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dc.publisher |
한국생체재료학회 |
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dc.title |
Genetically engineering encapsulin protein cage nanoparticle as a SCC-7 cell targeting optical nanoprobe |
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dc.type |
Article |
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dc.description.isOpenAccess |
TRUE |
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dc.description.journalRegisteredClass |
scopus |
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