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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 1032 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1027 | - |
dc.citation.title | CURRENT APPLIED PHYSICS | - |
dc.citation.volume | 12 | - |
dc.contributor.author | Lee, Il Buem | - |
dc.contributor.author | Lee, Ja Yil | - |
dc.contributor.author | Lee, Nam-Kyung | - |
dc.contributor.author | Hong, Seok-Cheol | - |
dc.date.accessioned | 2023-12-22T05:06:28Z | - |
dc.date.available | 2023-12-22T05:06:28Z | - |
dc.date.created | 2016-09-30 | - |
dc.date.issued | 2012-07 | - |
dc.description.abstract | In this report we investigated the effects of various biological and chemical factors (DNA sequence, pH, ions, and molecularity) on the formation of DNA triplexes through single-molecule FRET technique. Using this method, we determined how the third strand bound to a DNA duplex and how stable the triplex structure was under various conditions. From this study, we not only verified a variety of well-known features of DNA triplex but also discovered or experimentally supported several interesting behaviors: at neutral pH, a pyrimidine-motif triplex can be formed; the parallel arrangement was not only possible but also dominant over the antiparallel arrangement for a purine-motif triplex. We demonstrated that our method is a versatile analytical tool in studying structural aspects of nucleic acids, particularly non-classical DNA structures, and provides insights into physical mechanism of such structures. (C) 2012 Elsevier B. V. All rights reserved | - |
dc.identifier.bibliographicCitation | CURRENT APPLIED PHYSICS, v.12, no.4, pp.1027 - 1032 | - |
dc.identifier.doi | 10.1016/j.cap.2011.12.026 | - |
dc.identifier.issn | 1567-1739 | - |
dc.identifier.scopusid | 2-s2.0-84862812216 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/20500 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1567173911006249 | - |
dc.identifier.wosid | 000303129800005 | - |
dc.language | 영어 | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.title | Direct observation of the formation of DNA triplexes by single-molecule FRET measurements | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | DNA triplex | - |
dc.subject.keywordAuthor | H-DNA | - |
dc.subject.keywordAuthor | Single-molecule FRET | - |
dc.subject.keywordAuthor | pH | - |
dc.subject.keywordAuthor | Strand alignment | - |
dc.subject.keywordPlus | RECOGNITION | - |
dc.subject.keywordPlus | COMPLEX | - |
dc.subject.keywordPlus | PH | - |
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