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DC Field | Value | Language |
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dc.citation.endPage | 46493 | - |
dc.citation.number | 87 | - |
dc.citation.startPage | 46488 | - |
dc.citation.title | RSC ADVANCES | - |
dc.citation.volume | 4 | - |
dc.contributor.author | Kwon, Min Sang | - |
dc.contributor.author | Jang, Geunseok | - |
dc.contributor.author | Bilby, David | - |
dc.contributor.author | Milian-Medina, Begona | - |
dc.contributor.author | Gierschner, Johannes | - |
dc.contributor.author | Lee, Taek Seung | - |
dc.contributor.author | Kim, Jinsang | - |
dc.date.accessioned | 2023-12-22T03:09:34Z | - |
dc.date.available | 2023-12-22T03:09:34Z | - |
dc.date.created | 2016-06-20 | - |
dc.date.issued | 2014 | - |
dc.description.abstract | Chemiluminescence (CL) sensors can provide convenience and high sensitivity because they do not require an external excitation light source to produce a fluorescence signal. However, most CL based detection systems do not have a built-in self-signaling process, leading to inefficient and complex protocols due to the required multistep cascade reactions. Here, we develop a CL based sensory system with a built-in self-signaling feature by adapting the chemodosimeter concept. We found that a masking group incorporated to luminol efficiently suppresses the CL of luminol and that selective removal of the masking group by a target analyte can turn on the CL process, generating a sensitive fluorescence turn-on signal. Through systematic studies on newly devised TBS-luminol and TIPS-luminol, we optimized the molecular design parameters to achieve a highly sensitive and selective CL chemodosimeter. The optimized conditions rendered highly sensitive (Limit of Detection (LOD) = 18 nM) and selective fluoride sensing in aqueous environments. We anticipate that our new sensor system offers an efficient way to achieve highly sensitive, selective, and convenient CL turn-on detection of various important analytes | - |
dc.identifier.bibliographicCitation | RSC ADVANCES, v.4, no.87, pp.46488 - 46493 | - |
dc.identifier.doi | 10.1039/c4ra08182j | - |
dc.identifier.issn | 2046-2069 | - |
dc.identifier.scopusid | 2-s2.0-84907487319 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/19904 | - |
dc.identifier.url | http://pubs.rsc.org/en/Content/ArticleLanding/2014/RA/C4RA08182J#!divAbstract | - |
dc.identifier.wosid | 000342761800011 | - |
dc.language | 영어 | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Design principles of chemiluminescence (CL) chemodosimeter for self-signaling detection: luminol protective approach | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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