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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 1472 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1456 | - |
dc.citation.title | MOLECULAR BIOSYSTEMS | - |
dc.citation.volume | 5 | - |
dc.contributor.author | Lee, Semin | - |
dc.contributor.author | Brown, Alan | - |
dc.contributor.author | Pitt, William Ross | - |
dc.contributor.author | Higueruelo, Alicia Perez | - |
dc.contributor.author | Gong, Sungsam | - |
dc.contributor.author | Bickerton, George Richard | - |
dc.contributor.author | Schreyer, Adrian | - |
dc.contributor.author | Tanramluk, Duangrudee | - |
dc.contributor.author | Baylay, Alison | - |
dc.contributor.author | Blundell, Tom Leon | - |
dc.date.accessioned | 2023-12-22T08:12:13Z | - |
dc.date.available | 2023-12-22T08:12:13Z | - |
dc.date.created | 2016-03-29 | - |
dc.date.issued | 2009 | - |
dc.description.abstract | Here we review the use of informatics in structural interactomics, with particular emphasis on understanding interfacial contacts in the development of novel therapeutics and the interpretation of genetic variation. We describe the availability and applicability of structural databases of protein interactions which facilitate this endeavour. We demonstrate the applicability of a structural interactomics approach to the study of the fibroblast growth factor (FGF)-stimulated mitogen-activated protein kinase (MAPK) pathway | - |
dc.identifier.bibliographicCitation | MOLECULAR BIOSYSTEMS, v.5, no.12, pp.1456 - 1472 | - |
dc.identifier.doi | 10.1039/b906402h | - |
dc.identifier.issn | 1742-206X | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/18896 | - |
dc.identifier.url | http://pubs.rsc.org/en/Content/ArticleLanding/2009/MB/b906402h#!divAbstract | - |
dc.identifier.wosid | 000271727600008 | - |
dc.language | 영어 | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Structural interactomics: informatics approaches to aid the interpretation of genetic variation and the development of novel therapeutics | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | PROTEIN-PROTEIN INTERACTIONS | - |
dc.subject.keywordPlus | FIBROBLAST-GROWTH-FACTOR | - |
dc.subject.keywordPlus | STRUCTURE HOMOLOGY RECOGNITION | - |
dc.subject.keywordPlus | AMINO-ACID SUBSTITUTION | - |
dc.subject.keywordPlus | NON-SYNONYMOUS SNPS | - |
dc.subject.keywordPlus | DRUG DISCOVERY | - |
dc.subject.keywordPlus | INTERACTION NETWORKS | - |
dc.subject.keywordPlus | STABILITY CHANGES | - |
dc.subject.keywordPlus | FACTOR RECEPTOR | - |
dc.subject.keywordPlus | SACCHAROMYCES-CEREVISIAE | - |
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