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Bhak, Jong
The Genomics Institute of UNIST (TGI)
Research Interests
  • Geromics, genomics, bioinformatics, protein Engineering, OMICS

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Ancient Ethiopian genome reveals extensive Eurasian admixture throughout the African continent

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Title
Ancient Ethiopian genome reveals extensive Eurasian admixture throughout the African continent
Author
Gallego Llorente, M.Jones, E.R.Eriksson, A.Siska, V.Arthur, K.W.Arthur, J.W.Curtis, M.C.Stock, J.T.Coltorti, M.Pieruccini, P.Stretton, S.Brock, F.Higham, T.Park, Y.Hofreiter, M.Bradley, D.G.Bhak, Jong HwaPinhasi, R.Manica, A.
Issue Date
201511
Publisher
AMER ASSOC ADVANCEMENT SCIENCE
Citation
SCIENCE, v.350, no.6262, pp.820 - 822
Abstract
Characterizing genetic diversity in Africa is a crucial step for most analyses reconstructing the evolutionary history of anatomically modern humans. However, historic migrations from Eurasia into Africa have affected many contemporary populations, confounding inferences. Here, we present a 12.5×coverage ancient genome of an Ethiopian male (Mota) who lived approximately 4500 years ago. We use this genome to demonstrate that the Eurasian backflow into Africa came from a population closely related to Early Neolithic farmers, who had colonized Europe 4000 years earlier. The extent of this backflow was much greater than previously reported, reaching all the way to Central, West, and Southern Africa, affecting even populations such as Yoruba and Mbuti, previously thought to be relatively unadmixed, who harbor 6 to 7% Eurasian ancestry
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DOI
http://dx.doi.org/10.1126/science.aad2879
ISSN
0036-8075
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