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김성필

Kim, Sung-Phil
Brain-Computer Interface Lab.
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Adaptation of cortical activity to sustained pressure stimulation on the fingertip

Author(s)
Kim, Sung-PhilChung, Yoon GiHan, Sang WooKim, Hyung-SikChung, Soon-CheolPark, Jang-YeonWallraven, Christian
Issued Date
2015-10
DOI
10.1186/s12868-015-0207-x
URI
https://scholarworks.unist.ac.kr/handle/201301/17711
Fulltext
http://www.biomedcentral.com/1471-2202/16/71
Citation
BMC NEUROSCIENCE, v.16, pp.71
Abstract
Background
Tactile adaptation is a phenomenon of the sensory system that results in temporal desensitization after an exposure to sustained or repetitive tactile stimuli. Previous studies reported psychophysical and physiological adaptation where perceived intensity and mechanoreceptive afferent signals exponentially decreased during tactile adaptation. Along with these studies, we hypothesized that somatosensory cortical activity in the human brain also exponentially decreased during tactile adaptation. The present neuroimaging study specifically investigated temporal changes in the human cortical responses to sustained pressure stimuli mediated by slow-adapting type I afferents.

Methods
We applied pressure stimulation for up to 15 s to the right index fingertip in 21 healthy participants and acquired functional magnetic resonance imaging (fMRI) data using a 3T MRI system. We analyzed cortical responses in terms of the degrees of cortical activation and inter-regional connectivity during sustained pressure stimulation.

Results
Our results revealed that the degrees of activation in the contralateral primary and secondary somatosensory cortices exponentially decreased over time and that intra- and inter-hemispheric inter-regional functional connectivity over the regions associated with tactile perception also linearly decreased or increased over time, during pressure stimulation.

Conclusion
These results indicate that cortical activity dynamically adapts to sustained pressure stimulation mediated by SA-I afferents, involving changes in the degrees of activation on the cortical regions for tactile perception as well as in inter-regional functional connectivity among them. We speculate that these adaptive cortical activity may represent an efficient cortical processing of tactile information.
Publisher
BIOMED CENTRAL LTD
ISSN
1471-2202
Keyword (Author)
Somatosensory cortexTactile adaptationPressureFunctional connectivityfMRI
Keyword
SUPERIOR PARIETAL CORTEXCUTANEOUS MECHANORECEPTIVE AFFERENTSPRIMARY SOMATOSENSORY CORTEXVIBROTACTILE STIMULATIONFREQUENCY DISCRIMINATIONVIBRATORY ADAPTATIONPROBABILISTIC MAPSDEPENDENT RESPONSEHUMAN BRAINFMRI

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